171484-68-7Relevant academic research and scientific papers
A predictable enantioselective total synthesis of (+)-clavularin A
Weinmann,Winterfeldt
, p. 1097 - 1101 (1995)
Cycloadduct 9 was transformed into vinylsilane 11d in a conjugate addition-alkylation sequence. Epoxidation and subsequent hydrolysis provided the clavularin adduct 14, which on flash vacuum pyrolysis (FVP) gave (+)-clavularin A (1) in 91% yield.
