171485-39-5 Usage
Uses
Used in Pharmaceutical Industry:
Artemetin is used as an anti-malarial agent for its ability to treat malaria, a disease caused by Plasmodium parasites. Its traditional use in Chinese medicine has been validated by modern research, which has confirmed its efficacy in combating the disease.
Used in Oncology:
In the field of oncology, artemetin is used as a potential anti-cancer agent. It has demonstrated the capacity to inhibit the growth of various types of cancer cells, making it a subject of interest for further research and development in cancer treatment.
Used in Anti-inflammatory Applications:
Artemetin is utilized for its anti-inflammatory properties, which can be beneficial in managing inflammation-related conditions. Its ability to reduce inflammation may contribute to the treatment of a variety of diseases where inflammation plays a significant role.
Used in Antioxidant Formulations:
Given its antioxidant effects, artemetin is used in formulations aimed at neutralizing free radicals and preventing oxidative stress. This can be particularly useful in skincare products, dietary supplements, and medical treatments designed to protect against or mitigate oxidative damage.
Used in Traditional Chinese Medicine:
Artemetin continues to be used in traditional Chinese medicine for its fever-reducing properties. Its long history of use provides a foundation for its continued application in this field, particularly for conditions characterized by fever and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 171485-39-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,4,8 and 5 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 171485-39:
(8*1)+(7*7)+(6*1)+(5*4)+(4*8)+(3*5)+(2*3)+(1*9)=145
145 % 10 = 5
So 171485-39-5 is a valid CAS Registry Number.
171485-39-5Relevant academic research and scientific papers
Identification of a Novel TRPM8 Agonist from Nutmeg: A Promising Cooling Compound
Shirai, Tomohiro,Kumihashi, Kentaro,Sakasai, Mitsuyoshi,Kusuoku, Hiroshi,Shibuya, Yusuke,Ohuchi, Atsushi
, p. 715 - 719 (2017/07/22)
The transient receptor potential melastatin 8 (TRPM8) ion channel is the primary receptor for innocuous cold stimuli (8′-7-ethoxy-4-hydroxy-3,3′,5′-trimethoxy-8-O-4′-neolignan (1) with an EC50 of 0.332 μM, which was isolated from a well-known spice, nutmeg (Myristica fragrans Houtt.). Structure activity relationships are also disclosed, showing that the 7-d-menthoxy derivative is the most potent agonist (EC50 = 11 nM). The combination of 1 and l-(-)-menthol has an additive effect, suggesting that neolignan compounds interact with TRPM8 at different sites from those of l-(-)-menthol.
Asymmetric synthesis of the natural erythro-(1R,2S)-8-O-4′-neolignan myrislignan
Xia,Wang, Wei
, p. 93 - 96 (2011/10/01)
An efficient and practical asymmetric synthesis of erythro-(1R,2S)-8-O- 4′-neolignan myrislignan was achieved by using vanillin and pyrogallic acid as the starting materials. Two key steps are involved: preparation of an enantiopure threo alcohol of predictable stereochemistry by dihydroxylation with AD-mix-β, and inversion of the absolute configuration from the threo to the erythro isomer using a Mitsunobu reaction. The route illustrates a new methodology for the synthesis of erythro-8-O-4′-neolignan. Graphical abstract: [Figure not available: see fulltext.]
