(aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol

Base Information

Chemical Name:(aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol
CAS No.:171485-39-5
Molecular Formula:C₂₁H₂₆O₆
Molecular Weight:374.434
Hs Code.:
Mol file:171485-39-5.mol

Synonyms:Benzenemethanol,a-[1-[2,6-dimethoxy-4-(2-propenyl)phenoxy]ethyl]-4-hydroxy-3-methoxy-,[S-(R*,S*)]-;Myrislignan;

Suppliers and Price of (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Myrislignan
10mg
$ 452.00

JR MediChem
Myrislignan 98%
20mg
$ 1000.00

DC Chemicals
Myrislignan >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
Myrislignan 97%
50mg
$ 328.00

Crysdot
Myrislignan 97%
100mg
$ 572.00

Chemenu
Myrislignan 97%
100mg
$ 514.00

Biorbyt Ltd
Myrislignan >98%,Standard References Grade
20 mg
$ 569.50

AvaChem
Myrislignan
20mg
$ 269.00

AvaChem
Myrislignan
5mg
$ 129.00

Arctom
Myrislignan
20mg
$ 198.00

Total 43 raw suppliers

Chemical Property of (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol

Chemical Property:

Boiling Point:537.6±50.0 °C(Predicted)
PKA:9.94±0.31(Predicted)
PSA：77.38000
Density:1.167 g/cm³
LogP:3.64740

Purity/Quality:

98%,99%, ^*data from raw suppliers

Myrislignan ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol

There total 24 articles about (aR)-alpha-[(1S)-1-[2,6-Dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxybenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: C₂₃H₃₀O₇

: 171485-39-5
erythro-Δ^8’-4,7-dihydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; for 2.5h;
DOI:10.1021/acsmedchemlett.7b00104

Reference yield:

: C₂₈H₃₈O₈

: 171485-39-5
(-)?erythro?(7S,8R)?Δ^8′?4,7?dihydroxy?3,3',5'-tetramethoxy?8?O?4′?neolignan

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃; for 8h;
DOI:10.1007/s00706-010-0420-3

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 171485-39-5
erythro-Δ^8’-4,7-dihydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan

Guidance literature:: Multi-step reaction with 8 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 - 20 °C

2.1: diethyl ether; tetrahydrofuran / 0.5 h / 0 °C

3.1: manganese(IV) oxide / dichloromethane / 72 h / 20 °C

4.1: bromine / chloroform / 24 h / 20 °C

4.2: 72 h / 20 °C

5.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 - 20 °C

6.1: potassium carbonate / acetone / 18 h / 40 °C

7.1: 15-crown-5; sodium tetrahydroborate / methanol; isopropyl alcohol / 6 h

8.1: hydrogenchloride / tetrahydrofuran; water / 2.5 h / 0 °C

With 1H-imidazole; hydrogenchloride; manganese(IV) oxide; sodium tetrahydroborate; 15-crown-5; bromine; potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; chloroform; water; N,N-dimethyl-formamide; isopropyl alcohol; acetone; 2.1: |Grignard Reaction;
DOI:10.1021/acsmedchemlett.7b00104