17149-11-0Relevant academic research and scientific papers
Catalytic and selective conversion of glycine into serine by the reaction with formaldehyde in a neutral aqueous solution
Yashiro, Morio
, p. 1383 - 1384 (2002)
Di- or trinuclear Cu(II) complexes efficiently catalyzed the condensation of glycine with formaldehyde to yield serine at pH 7.3, 50°C.
Propionamide antitumor agents
-
, (2008/06/13)
The present invention encompasses compounds of the formula STR1 AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF WHEREIN R represents hydrogen or hydroxymethyl. The compounds of the present invention are prepared by condensing N-carbobenzyloxyserine or 2-carbobenzyloxyamino-3-hydroxy-2-hydroxymethylpropionic acid with p- N,N-bis(2-chloroethyl)!phenylenediamine hydrochloride and removing the carbobenzyloxy protecting group by catalytic hydrogenation. These compounds are useful as cytotoxic agents, in particular, antitumor agents.
