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171670-07-8

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171670-07-8 Usage

General Description

6-((tert-butoxycarbonylamino)methyl)picolinic acid is a chemical compound that is composed of a picolinic acid core with a tert-butoxycarbonylamino)methyl side chain. This molecule has a molecular formula of C13H18N2O5 and a molecular weight of 282.29 g/mol. It is commonly used as a building block in organic synthesis and peptide chemistry. The tert-butoxycarbonylamino group serves as a protecting group for the amine functionality, allowing for selective reactions to occur. 6-((tert-butoxycarbonylamino)methyl)picolinic acid is often utilized in the production of pharmaceuticals and agrochemicals, as well as in research and development of new chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 171670-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,6,7 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 171670-07:
(8*1)+(7*7)+(6*1)+(5*6)+(4*7)+(3*0)+(2*0)+(1*7)=128
128 % 10 = 8
So 171670-07-8 is a valid CAS Registry Number.

171670-07-8Downstream Products

171670-07-8Relevant articles and documents

Enhancing Aromatic Foldamer Helix Dynamics to Probe Interactions with Protein Surfaces

Vallade, Ma?lle,Sai Reddy, Post,Fischer, Lucile,Huc, Ivan

, p. 5489 - 5498 (2018)

Dynamic helices that undergo exchange between P and M conformations can be used as sensors when their interactions with chiral substances results in a helix handedness bias. For instance, chiral induction in short helically folded aromatic oligoamides based on 8-amino-2-quinoline carboxylic acid (Q) has been used to detect interactions with proteins and nucleic acids. However, the stability of these helices in water increases rapidly with oligomer length to the extent that helix dynamics become too slow for sensing applications. We have developed an approach to enhance the helix dynamics of these oligomers through the introduction of more flexible 6-aminomethyl-2-pyridinecarboxylic acid units (P) while preserving helix integrity. A series of P/Q hybrid oligoamides were synthesized and their rate of helix handedness inversion was evaluated by monitoring induced circular dichroism so as to define the requirements to bring kinetics in a practical range for sequences as long as fourteen units. Proof of principle was then brought by confining such sequences at the surface of carbonic anhydrase and showing that protein-mediated helix handedness induction occurs.

CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF

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Page/Page column 41, (2016/08/23)

The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.

4,6-DISUBSTITUTED PYRIMIDINES AND THEIR USE AS PROTEIN KINASE INHIBITORS

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Page/Page column 56, (2008/06/13)

The invention relates to novel pyrimidine derivatives of Formula (I), which are efficacious inhibitors of protein kinases, in particular of one or more isoforms of the protein kinase B/Akt.

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