171673-60-2Relevant academic research and scientific papers
Highly efficient Fe(HSO4)3-catalyzed one-pot mannich-type reactions: Three component synthesis of β-amino carbonyl compounds
Eshghi, Hossein,Alipour, Afsaneh,Damavandi, Saman
, p. 266 - 271 (2011)
Fe(HSO4)3-catalyzed three-component one-pot Mannich reaction of acetophenone with different aromatic aldehydes and aromatic amines in ethanol at ambient temperature afforded the corresponding β-aminocarbonyl compounds in very good to excellent yields. Short reaction time, excellent yield, easy work-up procedure, applicability of using various amines and aldehydes, capability of conversion of ortho-substituted aromatic amines to the corresponding Mannich base in satisfying yields, and eventually high reusability of the catalyst show the merit of this study. Copyright Taylor & Francis Group, LLC.
