17170-26-2

Usage

Uses

Used in Organic Synthesis:
2-(7-Octyn-1-yl)-1H-isoindole-1,3-dione is used as a building block in organic synthesis for the creation of various organic compounds. Its unique structure allows for the formation of new chemical entities with potential applications in different fields.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-(7-Octyn-1-yl)-1H-isoindole-1,3-dione serves as a key component in the synthesis of pharmaceutical drugs. Its structural features facilitate the development of novel therapeutic agents with improved efficacy and selectivity.
Used in the Development of New Materials:
2-(7-Octyn-1-yl)-1H-isoindole-1,3-dione is utilized in the development of innovative materials due to its conjugated system and alkyne functionality. These properties enable the creation of materials with unique properties and potential applications in various industries.
Used in the Study of Biological Systems:
2-(7-Octyn-1-yl)-1H-isoindole-1,3-dione is also used in biological research to study the interactions between molecules and biological systems. Its structural features make it a valuable tool for understanding complex biological processes and developing new therapeutic strategies.
Overall, 2-(7-Octyn-1-yl)-1H-isoindole-1,3-dione is a promising compound with a wide range of applications in scientific and industrial settings, from the synthesis of new compounds to the development of advanced materials and pharmaceuticals.

Upstream product

• 81216-13-9 8-bromooct-1-yne 
• 1074-82-4 potassium phtalimide 
• 871-91-0 oct-7-yn-1-ol 

Downstream Products

• 14502-43-3 8-aminooct-1-yne 

Relevant academic research and scientific papers

Azerocyclic compounds and their uses

The present invention proposes a nitrogen heterocyclic compound and its use, in particular, the present invention proposes a new compound that effectively inhibits ATX, which is a compound shown in the formula below, or a tautomer of the compound shown be

Very contracted to extended co -conformations with or without oscillations in two- and three-station ['2]daisy chains

The syntheses of various two- and three-station mannosyl [c2]daisy chains, based on a dibenzo-24-crown-8 macrocyclic moiety and an ammonium, a triazolium, and a mono- or disubstituted pyridinium amide station, are reported. The ability of these molecules to act as molecular machine based mimetics has been further studied by 1H NMR studies. In all the protonated ammonium states, the interwoven rotaxane dimers adopt an extended co-conformation. However, carbamoylation of the ammonium station led to many different other [c2]daisy chain co-conformations, depending on the other molecular stations belonging to the axle. In the two-station [c2]daisy chains containing an ammonium and a mono- or disubstituted pyridinium amide station, two large-amplitude relative movements of the interwoven components were noticed and afforded either an extended and a contracted or very contracted state with, in the latter case, an impressive chairlike conformational flipping of the mannopyranose from 1C4 to 4C1. In the case of the three-station-based [c2]daisy chains containing an ammonium, a triazolium, and disubstituted pyridinium amide, an extended and a half-contracted molecular state could be obtained because of the stronger affinity of the dibenzo-24-crown-8 part for, respectively, the ammonium, the triazolium, and the disubstituted pyridinium amide. Eventually, with axles comprising an ammonium, a triazolium, and a monosubstituted pyridinium amide, an extended conformation was noticed in the protonated state whereas a continuous oscillation between half-contracted and contracted states, in fast-exchange on the NMR time scale, was triggered by carbamoylation. Variations of the solvent or the temperature allow the modification of the population of each co-conformer. Thermodynamic data provided a small free Gibbs energy δG of 2.1 kJ·mol -1 between the two translational isomers at 298 K.

A new pH-switchable dimannosyl[c2]daisy chain molecular machine

(Figure Presented) The preparation of a dimannosyl[c2]daisy chain molecular machine containing an ammonium and a triazolium station is described. The both stretched and contracted states of the molecular machine can be obtained by variation of the pH, thus localizing the mannosyl stoppers closer or farther away.