171754-02-2

Basic information

• Product Name: (3S)-2-AZABICYCLO(2.2.1)HEPTANE-3-CARBO
• Synonyms: (3S)-2-AZABICYCLO(2.2.1)HEPTANE-3-CARBO
• CAS NO: 171754-02-2
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.23
• Mol File: 171754-02-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3S)-2-AZABICYCLO(2.2.1)HEPTANE-3-CARBO(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-2-AZABICYCLO(2.2.1)HEPTANE-3-CARBO(171754-02-2)
• EPA Substance Registry System: (3S)-2-AZABICYCLO(2.2.1)HEPTANE-3-CARBO(171754-02-2)

Safety Data

• Hazardous Substances Data: 171754-02-2(Hazardous Substances Data)

Usage

General Description

(3S)-2-Azabicyclo(2.2.1)heptane-3-carbo, also known as tropanes, are a class of organic compounds containing a bicyclic structure with a nitrogen atom. Tropanes are commonly found in various alkaloids, including cocaine, atropine, and scopolamine. They have a range of pharmacological effects, including anticholinergic, sympathomimetic, and local anesthetic properties. These chemicals are highly potent and have been widely studied for their potential medicinal uses, as well as their addictive and harmful effects. Additionally, tropane derivatives have also been investigated as potential pharmaceutical agents for the treatment of various conditions, including neurological and psychiatric disorders.

Upstream product

• 204327-17-3 (1S,3R,4R)-2-aza-bicyclo<2.2.1>heptane-3-carboxylic acid ethyl ester 
• 223505-12-2 (1R,3R,4S)-2-<(1S)-phenylethyl>-2-aza-bicyclo<2.2.1>hept-5-ene-3-carboxylic acid ethyl ester 
• 542-92-7 cyclopenta-1,3-diene 
• 130194-96-6 (1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester 
• 134984-63-7 (1S,3S,4R)-2-((R)-1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid ethyl ester 
• 214910-41-5 (1R,3S,4S)-2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid ethyl ester 
• 192461-70-4 ethyl (1R,3S,4S)-2-<(R)-1-phenylethyl>-2-azabicyclo<2.2.1>heptane-3-exo-carboxylate 
• 171563-64-7 (1S,3S,4R)-2-((R)-1-Phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid benzyl ester 

Downstream Products

• 134877-62-6 (1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 
• 700867-42-1 (1S,3R,4R)-3-(4',5'-dihydro-5',5'-dimethyl-1',3'-oxazol-2'-yl)-2-aza-bicyclo-[2.2.1]-heptane 
• 134795-25-8 (1R,3S,4S)-2-aza-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid 2-tert-butyl ester 
• 1246090-88-9 2-((1S,3R,4R)-2-azabicyclo[2.2.1]heptan-3-yl)-4-phenylthiazole 
• 791613-42-8 (1S,3R,4R)-3-(4',5'-dihydro-5',5'-diphenyl-1',3'-oxazol-2'-yl)-2-azabicyclo[2.2.1]heptane 
• 1246090-86-7 (1S,3R,4R)-tert-butyl 3-(4-phenylthiazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate 
• 791613-41-7 (1S,3R,4R)-3-(4',5'-dihydro-5',5'-diphenyl-1',3'-oxazol-2'-yl)-2-azabicyclo[2.2.1]heptane-2-N-carboxylic acid p-nitrobenzyl ester 
• 791613-40-6 (1S,3R,4R)-3-(2'-hydroxy-1',1'-diphenylethylcarbamoyl)-2-azabicyclo[2.2.1]heptane-2-N-carboxylic acid p-nitrobenzyl ester 
• 291775-53-6 (1S,3R,4R)-N-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 

Relevant articles and documents

Application of polyamines and amino acid derivatives based on 2-azabicycloalkane backbone in enantioselective aldol reaction

Carbon–carbon bond forming reactions, such as aldol reaction and condensation, belong to extremely desired transformations as manifested by >25,000 entries in SciFinder. Their stereoselective variant requires the use of an appropriate catalyst with a stri

HEPATITIS C VIRUS INHIBITORS

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Synthesis of fragments of transforming growth factor alpha incorporating exo-2-azabicyclo[2,2,1 ]heptane-3-carboxylic acids as proline substitutes

Two novel amino acids, the enantiomers ofexo 2-azabicyclo [2,2,1]heptane-3-carboxylic acid have been independent synthesized by the aza Diels Alder reaction using a chiral auxiliary. The two acids have been advanced via solid phase synthesis to afford linear sequences, which have been cyclized to afford cyclic disulfide peptides, analogues of fragments of TGFd. The structures of these and other fragments have been firmly established.