171764-50-4Relevant articles and documents
Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology
Meerpoel, Lieven,Backx, Leo J. J.,Van Der Veken, Louis J. E.,Heeres, Jan,Corens, David,De Grout, Alex,Odds, Frank C.,Van Gerven, Frans,Woestenborghs, Filip A. A.,Van Breda, Andre,Oris, Michel,Van Dorsselaer, Pascal,Willemsens, Gustaaf H. M.,Vermuyten, Karen J. P.,Marichal, Patrick J. M. G.,Vanden Bossche, Hugo F.,Ausma, Jannie,Borgers, Marcel
, p. 2184 - 2193 (2007/10/03)
In search for new compounds with potential for clinical use as antifungal agents in dermatology, a series of 12 azole compounds were synthesized stereospecifically and investigated specifically for their activity against dermatophyte fungal infections in
[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
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, (2008/06/13)
Novel [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles, having anti-microbial activity, compositions containing the same, and methods of inhibiting and/or eliminating the development of fungi and