171858-07-4

Basic information

• Product Name: 4-Hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-butan-1-one
• CAS NO: 171858-07-4
• Molecular Weight: 167.208
• Mol File: 171858-07-4.mol

Chemical Properties

• CAS DataBase Reference: 4-Hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-butan-1-one(171858-07-4)
• EPA Substance Registry System: 4-Hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-butan-1-one(171858-07-4)

Safety Data

• Hazardous Substances Data: 171858-07-4(Hazardous Substances Data)

Upstream product

• 96-54-8 N-Methylpyrrole 
• 96-48-0 4-butanolide 

Relevant articles and documents

A dichotomy in the Friedel-Crafts reaction of lactones provides a convenient new route to 2-acylated pyrroles and tetrahydroindolones

In striking contrast to arenes, N-methylpyrrole undergoes Friedel-Crafts acylation with lactones. The reaction is most efficient with γ- and δ-lactones; ε-lactones proceed with poor overall conversion while β-lactones display poor selectivity. γ-Alkyl-γ-lactones readily yield 4,5,6,7-tetrahydroindol-7-ones through a sequence analogous to the Truce-Olson annulation.