171922-32-0

Basic information

• Product Name: 4-Pentenoic acid, 2-[(diphenylmethylene)amino]-2-(2-propynyl)-, ethyl ester
• CAS NO: 171922-32-0
• Molecular Formula: C23H23NO2
• Molecular Weight: 345.441
• Mol File: 171922-32-0.mol

Chemical Properties

• CAS DataBase Reference: 4-Pentenoic acid, 2-[(diphenylmethylene)amino]-2-(2-propynyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 2-[(diphenylmethylene)amino]-2-(2-propynyl)-, ethyl ester(171922-32-0)
• EPA Substance Registry System: 4-Pentenoic acid, 2-[(diphenylmethylene)amino]-2-(2-propynyl)-, ethyl ester(171922-32-0)

Safety Data

• Hazardous Substances Data: 171922-32-0(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 171922-16-0 ethyl 2-[(diphenylmethylidene)amino]pent-4-ynoate 
• 115289-57-1 ethyl N-(diphenylmethylene)-2-amino-4-pentenoate 
• 106-96-7 propargyl bromide 
• 69555-14-2 ethyl N-diphenylmethylene glycine 

Downstream Products

• 1044756-13-9 C₂₃H₂₃NO₂ 
• 207294-54-0 ethyl 1-acetamido-3-cyclopentene-3-vinyl-1-carboxylate 

Relevant articles and documents

Catalytic Generation of Rhodium Silylenoid for Alkene-Alkyne-Silylene [2 + 2 + 1] Cycloaddition

An alkene-alkyne-silylene [2 + 2 + 1] cycloaddition takes place in the rhodium-catalyzed reaction of 1,6-enynes with borylsilanes bearing an alkoxy group on the silicon atoms, which react as synthetic equivalents of silylene. The reaction proceeds efficiently in 1,2-dichloroethane at 80-110 °C in the presence of a rhodium catalyst bearing bis(diphenylphosphino)methane (DPPM) as a ligand to afford 1-silacyclopent-2-enes in good to high yields.

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Ethyl N-(diphenylmethylene)glycinate, 1, undergoes monoalkylations, dialkylations and Michael additions to ethylenic and acetylenic acceptors under appropriate solid-liquid phase transfer catalysis conditions. Further transformations of the α-disubstituted ketimines lead to α-alkylated aspartic and glutamic acid derivatives 10, 15, 19 and 26, to bicyclic amino acids or derivatives featuring pyrazolone and isoxazolone moieties 30 and 33, and to α-substituted (E)-3,4-dehydroglutamic acids. Copyright

Ethyl N-(Diphenylmethylene)glycinate as Anionic Glycine Equivalent Transition Metal Mediated Preparation of Bicyclic and Tricyclic α,α-Disubstituted α-Amino Acids and Derivatives

Synthetic approaches to bicyclic and tricyclic α,α-disubstituted α-amino acids and derivatives 6, 8, 10, 12, 13, 21, 22, 23, 24, 28, 30, and 31 are presented.Methyl acetoacetate, ethyl nitroacetate, and ethyl N-(diphenylmethylene)glycinate are compared as