172213-38-6

Basic information

• Product Name: (2S,3R,E)-1-(tert-butyldiphenylsilyloxy)-2-(N-tertbutyloxycarbonyl)aminooctadec-4-en-3-ol
• Synonyms: (2S,3R,E)-1-(tert-butyldiphenylsilyloxy)-2-(N-tertbutyloxycarbonyl)aminooctadec-4-en-3-ol
• CAS NO: 172213-38-6
• Molecular Weight: 638.019
• Mol File: 172213-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S,3R,E)-1-(tert-butyldiphenylsilyloxy)-2-(N-tertbutyloxycarbonyl)aminooctadec-4-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,E)-1-(tert-butyldiphenylsilyloxy)-2-(N-tertbutyloxycarbonyl)aminooctadec-4-en-3-ol(172213-38-6)
• EPA Substance Registry System: (2S,3R,E)-1-(tert-butyldiphenylsilyloxy)-2-(N-tertbutyloxycarbonyl)aminooctadec-4-en-3-ol(172213-38-6)

Safety Data

• Hazardous Substances Data: 172213-38-6(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 609812-03-5 tert-butyl (3E,1R,2S)-N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-carbamate 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 6036-75-5 (2R,3S,4E)-2-aminooctadec-4-ene-1,3-diol 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 122709-20-0 N-(tert-butoxycarbonyl)-L-serine N'-methoxy-N'-methylamide 
• 13360-61-7 1-pentadecene 
• 116467-63-1 N-tert-butyloxycarbonylsphingosine 

Downstream Products

• 263543-27-7 C₄₂H₆₇NO₄Si 
• 378756-01-5 (2S,3R,4E)-2-amino-1-(tert-butyldiphenylsilanyloxy)octadec-4-en-3-ol 

Relevant articles and documents

Enantioselective Synthesis of Aminodiols by Sequential Rhodium-Catalysed Oxyamination/Kinetic Resolution: Expanding the Substrate Scope of Amidine-Based Catalysis

Regio- and stereoselective oxyamination of dienes through a tandem rhodium-catalysed aziridination–nucleophilic opening affords racemic oxazolidinone derivatives, which undergo a kinetic resolution acylation process with amidine-based catalysts (ABCs) to achieve s values of up to 117. This protocol was applied to the enantioselective synthesis of sphingosine.

Caged ceramide 1-phosphate analogues: Synthesis and properties

(Chemical Equation Presented) Sphingolipid phosphate analogues bearing 7-(diethylamino)-coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl (BHNB) groups in a photolabile ester bond were synthesized. The ability of the "caged" ceramide 1-phosphate analogues to release the bioactive parent molecule upon irradiation at 400-500 nm was demonstrated by stimulation of macrophage cell proliferation. 2009 American Chemical Society.