172218-35-8Relevant academic research and scientific papers
Haloarenes in the Duff reaction under high pressures 2. Formylation and amidomethylation of haloarenes in trifluoroacetic acid
Sedishev, I. P.,Agafonov, N. E.,Kutin, A. A.,Zhulin, V. M.
, p. 2127 - 2130 (2007/10/03)
Reactions of haloarenes with urotropine in CF3COOH at elevated temperatures and high pressures give the corresponding aromatic aldehydes and/or N-(haloarylmethyl)trifluoroacetamides.The yields of the products and their ratio depend on electronic properties of substituents in the aromatic ring.The reaction carried out in a mixture of CF3COOH and (CF3CO)2O affords only amides. - Keywords: haloarenes; Duff reaction; high pressure; haloarenecarbaldehydes; N-(haloarylmethyl)trifluoroacetamides.
