172324-64-0

Basic information

• Product Name: 9-adenine
• CAS NO: 172324-64-0
• Molecular Weight: 309.371
• Mol File: 172324-64-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-adenine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-adenine(172324-64-0)
• EPA Substance Registry System: 9-adenine(172324-64-0)

Safety Data

• Hazardous Substances Data: 172324-64-0(Hazardous Substances Data)

Upstream product

• 132089-80-6 6-(4-chlorophenylsulfanyl)-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine 
• 100-51-6 benzyl alcohol 
• 172324-70-8 (1r,3r)-3-((benzyloxy)methyl)cyclobutyl 4-nitrobenzoate 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 
• 172324-68-4 (1s,3s)-3-((benzyloxy)methyl)cyclobutanol 
• 172324-65-1 (1r,3r)-3-((benzyloxy)methyl)cyclobutanol 
• 5457-98-7 6-(4-chlorophenylsulfanyl)-9H-purine 
• 172324-66-2 3-(benzyloxymethyl)-2,2-dichlorocyclobutanone 
• 14593-43-2 benzyl allyl ether 
• 172324-63-9 9--6-(4-chlorophenylsulfanyl)-9H-purine 

Downstream Products

• 125962-36-9 9-adenine 

Relevant articles and documents

Synthesis of 9--adenine and -guanine

2,2-Dichloro-3-(benzyloxymethyl)cyclobutanone 15, which was prepared in 50percent yield by the cycloaddition of dichloroketene to allyl benzyl ether 14, was converted in four steps and in ca. 40percent overall yield into trans-3-(benzyloxymethyl)cyclobutanol 11b.The latter alcohol 11b was coupled under Mitsunobu conditions with 6-(4-chlorophenylsulfanyl)-9H-purine 21b and 6-(4-chlorophenylsulfanyl)-2-(phenylacetamido)-9H-purine 21c to give the 9-cyclobutylpurine derivatives 22 and 24, respectively, in 88 and 60percent yield.The former product 22 was converted in three steps and in 39percent overall yield into 9-adenine 6, and the latter product was converted in four steps and in 42percent overall yield into 9-guanine 7.X-Ray crystallographic data relating to compounds 22 and 24 are also reported.