172360-83-7

Upstream product

• 124477-12-9 2,6-anhydro-5-deoxy-3,4-O-isopropylidene-D-arabino-hex-5-enitol 
• 172360-81-5 2-(Trimethylsilyl)ethyl 2,3,6-tri-O-benzyl-4-O-(6-O-benzoyl-2-deoxy-2-iodo-3,4-O-isopropylidene-β-D-galactopyranosyl)-β-D-glucopyranoside 
• 172360-80-4 6-O-benzoyl-3,4-di-O-isopropylidene-D-galactal 
• 172360-82-6 2-(Trimethylsilyl)ethyl 2,3,6-tri-O-benzyl-4-O-(6-O-benzoyl-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl)-β-D-glucopyranoside 
• 117253-05-1 2-(trimethylsilyl)ethyl 2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 98-88-4 benzoyl chloride 

Downstream Products

• 172360-79-1 2-(Trimethylsilyl)ethyl 2,3,6-tri-O-benzyl-4-O-(3,6-di-O-benzoyl-2-deoxy-β-D-lyxo-hexopyranosyl)-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of Double-Chain Bis-sulfone Neoglycolipids of the 2'-, 3'-, and 6'-Deoxyglobotrioses

Partially protected 2-(trimethylsilyl)ethyl deoxylactosides (deoxygenated in the 2-, 3-, and 6-positions of the galactose unit) were synthesized via various routes and glycosylated with galactosyl donors to give the corresponding deoxytrisaccharides.Removal of the protecting groups gave the 2-(trimethylsilyl)ethyl 2'-, 3'-, and 6'-deoxyglobotriosides.Transformation of the protected trisaccharides into trichloroacetimidates, via the corresponding hemiacetals, proceeded in 86 - 96percent overall yield.Glycosylation of 3-(hexadecylsulfonyl)-2-propanol with the trisaccharidic trichloroacetimidates, in 37 - 68percent yield, followed by removal of protecting groups, gave the title neoglycolipids.