17241-40-6

Basic information

• Product Name: 2-Hydroxy-3-methylanthraquine
• Synonyms: 2-Hydroxy-3-methylanthraquine;2-Hydroxy-3-Methylanthraquinone;2-Hydroxy-3-Methylanthracene-9,10-dione
• CAS NO: 17241-40-6
• Molecular Formula: C₁₅H₁₀O₃
• Molecular Weight: 238.2381
• Mol File: 17241-40-6.mol

Chemical Properties

• Melting Point: 299 °C
• Boiling Point: 439.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.371±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 7.77±0.20(Predicted)
• CAS DataBase Reference: 2-Hydroxy-3-methylanthraquine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-3-methylanthraquine(17241-40-6)
• EPA Substance Registry System: 2-Hydroxy-3-methylanthraquine(17241-40-6)

Safety Data

• Hazardous Substances Data: 17241-40-6(Hazardous Substances Data)

Usage

Uses

Used in Dye Industry:
2-Hydroxy-3-methylanthraquinone is used as a dye intermediate for the production of reactive dyes and pigments. Its chemical structure allows it to be a key component in the synthesis of various dyes, contributing to the colorfastness and stability of the final products.
Used in Pharmaceutical Industry:
2-Hydroxy-3-methylanthraquinone is studied for its potential pharmaceutical properties, including antibacterial and antifungal activities. Its ability to inhibit the growth of harmful microorganisms makes it a promising candidate for the development of new antimicrobial agents.
Used in Medicinal and Cosmetic Products:
2-Hydroxy-3-methylanthraquinone has been shown to exhibit antioxidant and anti-inflammatory effects, making it a potentially valuable compound in the development of medicinal and cosmetic products. Its antioxidant properties can help protect cells from damage caused by free radicals, while its anti-inflammatory effects can contribute to the treatment of various skin conditions and inflammation-related disorders.

Upstream product

• 85-44-9 phthalic anhydride 
• 602-49-3 2-(4,4'-dihydroxy-3,3'-dimethyl-benzhydryl)-benzoic acid 
• 95-48-7 ortho-cresol 
• 17241-42-8 2-methoxy-3-methyl-9,10-anthraquinone 
• 51671-71-7 2-(3-methyl-4-methoxybenzoyl) benzoic acid 
• 17241-41-7 3-acetoxy-2-methylanthraquinone 
• 1010-60-2 2-chloro-1,4-naphthoquinone 
• 63446-78-6 (E)-2-methyl-1,3-bis(trimethylsiloxy)-buta-1,3-diene 
• 7664-93-9 sulfuric acid 
• 596-27-0 o-cresolphthalein 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 7446-70-0 aluminium trichloride 
• 14684-09-4 2-chloro-3-methyl-anthraquinone 

Downstream Products

• 613-12-7 2-methylanthracene 
• 75313-49-4 1,2-dimethoxy-3-methyl-anthraquinone 

Relevant articles and documents

Regiospecific Reactions of Some Vinylogous Ketene Acetals with Haloquinones and Their Regioselective Formation by Dienolization

Regiospecific reactions of simple 1,3-bis(trimethylsiloxy)-1,3-butadienes with 2,5- and 2,6-dichlorobenzoquinones gave chloronaphthoquinones which, by applying the appropriate vinylketene acetal, provided various monomethyl ethers of isomeric polyhydroxyanthraquinones.The first total synthesis of macrosporin (27) was obtained in this way and the proposed structure for "cajaquinone" (28) found to be incorrect.Simple syntheses of 2-hydroxy-3-methylanthraquinone (16), phomarin (19), soranjidiol (22) and other naturally occuring quinones are also described.The dienolization of 1-methoxy-2,4-pentanedione in the presence of chlorotrimethylsilane gave either 1- or 5-methoxy-2,4-bis(trimethylsiloxy)-1,3-pentadiene, depending upon the reaction conditions.Both dienes react with haloquinones, giving regiospecific products, e.g., tetra-O-methylerythrolaccin (35).

Preparation of naturally occurring anthraquinones

Several anthraquinones, which occur in plants used to treat cancer in traditional Chinese Medicine, have been synthesized and tested for cytotoxicity in two mammalian cell lines.