172455-28-6

Basic information

• Product Name: 4-cyano-5-(4-oxo-4H-pyridin-1-yl)-1,2-phenylenediamine
• Synonyms: 4-cyano-5-(4-oxo-4H-pyridin-1-yl)-1,2-phenylenediamine
• CAS NO: 172455-28-6
• Molecular Weight: 226.238
• Mol File: 172455-28-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyano-5-(4-oxo-4H-pyridin-1-yl)-1,2-phenylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-5-(4-oxo-4H-pyridin-1-yl)-1,2-phenylenediamine(172455-28-6)
• EPA Substance Registry System: 4-cyano-5-(4-oxo-4H-pyridin-1-yl)-1,2-phenylenediamine(172455-28-6)

Safety Data

• Hazardous Substances Data: 172455-28-6(Hazardous Substances Data)

Upstream product

• 172455-36-6 2-chloro-4-amino-5-nitrobenzonitrile 
• 626-64-2 pyridin-4-ol 
• 172455-27-5 4-cyano-3-(4-oxo-4H-pyridin-1-yl)-6-nitroaniline 
• 7439-89-6 iron 

Relevant articles and documents

Oxopyridinylquinoxaline derivative

An oxopyridinylquinoxaline derivative represented by the following Formula I or pharmaceutically acceptable salts thereof: STR1 wherein R 1 is hydrogen, halogen, nitro, or trihalomethyl; R 2 is hydrogen, halogen, nitro, cyano, trihalomethyl, carbamoyl, carbamoyl substituted with lower alkyl, sulfamoyl, or sulfamoyl substituted with lower alkyl; R 3 is hydrogen, nitro, or halogen; R 4 is hydrogen, lower alkyl, substituted lower alkyl, lower cycloalkyl, or substituted lower cycloalkyl; R 5 ''s are substituents independently selected from the group consisting of halogen, nitro, cyano, lower alkyl, carbamoyl, and carbamoyl substituted with lower alkyl; and n is an integer of 0 to 4. The derivative works as an antagonistic agent against both the NMDA receptors and the AMPA receptors, so that it is effective as a therapeutic agent for neurological disorders caused by excitatory amino acids binding to the receptors.