172469-91-9

Basic information

• Product Name: ethyl 4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
• Synonyms: 3-Pyridinecarboxylic acid, 4-((3,5-dimethylphenyl)thio)-5-ethyl-1,2-dihydro-6-methyl-2-oxo-, ethyl ester; 3-Pyridinecarboxylic acid, 4-[(3,5-dimethylphenyl)thio]-5-ethyl-1,2-dihydro-6-methyl-2-oxo-, ethyl ester; 3-pyridinecarboxylic acid, 4-[(3,5-dimethylphenyl)thio]-5-ethyl-2-hydroxy-6-methyl-, ethyl ester; ethyl 4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-2-hydroxy-6-methylpyridine-3-carboxylate
• CAS NO: 172469-91-9
• Molecular Formula: C₁₉H₂₃NO₃S
• Molecular Weight: 345.4558
• Mol File: 172469-91-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 496.4°C at 760 mmHg
• Flash Point: 254°C
• Density: 1.18g/cm³
• Vapor Pressure: 5.44E-10mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: ethyl 4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate(172469-91-9)
• EPA Substance Registry System: ethyl 4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate(172469-91-9)

Safety Data

• Hazardous Substances Data: 172469-91-9(Hazardous Substances Data)

Upstream product

• 38360-81-5 3,5-Dimethylthiophenol 
• 172469-74-8 4-chloro-5-ethyl-6-methyl-3-carbethoxypyridin-2(1H)-one 
• 172470-04-1 ethyl 5-ethyl-4-hydroxy-6-methyl-2-oxo-1H-pyridine-3-carboxylate 
• 607-97-6 ethyl 2-ethyl-3-oxobutanoate 
• 42805-39-0 ethyl (Z)-3-amino-2-ethyl-but-2-enoate 

Downstream Products

• 172470-05-2 5-ethyl-6-methyl-4-(3', 5'-dimethylphenyl)thio-pyridin-2(1H)-one 

Relevant articles and documents

A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors

4-(Arylthio)-pyridin-2(1H)-ones variously substituted in their 3-, 5-, and 6-positions have been synthesized as a new series of 1-[(2- hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)-pyridinone hybrid molecules. Biological studies revealed that some of them show potent HIV-1 specific reverse transcriptase inhibitory properties. Compounds 16 and 7c, the most active ones, inhibit the replication of HIV-1 at 3 and 6 nM, respectively.