17249-62-6

Usage

Uses

Used in Chemical Research:
(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanone is used as a research compound for exploring its chemical properties and potential applications in various fields. (5-HYDROXY-1-BENZOFURAN-3-YL)(PHENYL)METHANONE's unique structure, which combines benzofuran and phenyl groups, may offer insights into new chemical reactions or interactions with other molecules.
Used in Pharmaceutical Development:
(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanone is used as a starting material or intermediate in the synthesis of pharmaceutical compounds. Its structure may provide a basis for the development of new drugs, particularly in the context of its potential interactions with biological targets.
Used in Material Science:
(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanone is used as a component in the development of new materials, such as polymers or composites, that may exhibit unique properties due to the presence of the benzofuran and phenyl groups. (5-HYDROXY-1-BENZOFURAN-3-YL)(PHENYL)METHANONE's potential to form new chemical bonds or participate in reactions could contribute to the creation of innovative materials with specific applications.
Note: Since the compound is not widely studied or commonly used, the above uses are speculative and based on the potential of its chemical structure. Further research and development would be necessary to fully understand and exploit its applications in various industries.

InChI:InChI=1/C15H10O3/c16-11-6-7-14-12(8-11)13(9-18-14)15(17)10-4-2-1-3-5-10/h1-9,16H

Upstream product

• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 106-51-4 p-benzoquinone 
• 98-86-2 acetophenone 

Downstream Products

• 88673-85-2 (4-Chloro-5-hydroxy-benzofuran-3-yl)-phenyl-methanone 
• 88673-79-4 (4-Bromo-5-hydroxy-benzofuran-3-yl)-phenyl-methanone 
• 88673-82-9 (4,6-Dibromo-5-hydroxy-benzofuran-3-yl)-phenyl-methanone 
• 88673-87-4 (5-Hydroxy-4,6-dinitro-benzofuran-3-yl)-phenyl-methanone 
• 344868-28-6 Acetic acid 3-benzoyl-benzofuran-5-yl ester 
• 1254339-02-0 3-benzoyl-benzofuran-4,5-dione 
• 1442656-16-7 C₁₆H₁₄N₂O₂ 
• 1442656-17-8 methyl 2-[4-hydroxy-3-(3-phenyl-1H-pyrazol-4-yl)phenoxy]acetate 
• 1442656-18-9 ethyl 2-[4-hydroxy-3-(3-phenyl-1H-pyrazol-4-yl)phenoxy]acetate 
• 1442656-13-4 2-(3-phenyl-1H-pyrazol-4-yl)benzene-1,4-diol 
• 1441074-91-4 ethyl 2-(3-benzoylbenzofuran-5-yloxy)acetate 
• 1251913-23-1 methyl 2-(3-benzoylbenzofuran-5-yloxy)acetate 
• 19303-49-2 (5-methoxy-benzofuran-3-yl)-phenyl-methanone 
• 1001434-11-2 3-benzoyl-5-benzofuranyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside 

Relevant academic research and scientific papers

Amberlyst-15 in PEG-400: Green synthesis of 3-benzoyl-5-hydroxy benzofuran and naphtho[1,2-b]furan derivatives at room temperature

Background: Oxygen heterocycles exhibit diverse biological and pharmacological activities. In particular, benzofurans are available in a wide number of natural products and have drawn considerable attention over the last few years due to their profound physiological and biological properties. The aim of this paper describes a green methodology to synthesize this potent molecule with high selectivity by using ionic resin in PEG at room temperature. Methods: The methodology is very simple and easily accessible at room temperature. It uses low catalyst loadings and is recycled subsequently. In addition, detailed experimental procedure for the selected compounds including the spectral data are provided. Results: Among the various ionic resins attempted, Amberlyst-15 in PEG-400 was the choice of selection for the synthesis of 3-benzoyl-5-hydroxy benzofuran and naphtho[1,2-b]furan derivatives at room temperature in an environmentally friendly method. This catalyst system resulted in excellent yields in short reaction times and high selectivity. Conclusion: We have developed a green highly efficient and environmentally friendly protocol for the facile synthesis of 3-benzoyl-5-hydroxy benzofuran and naphtho[1,2-b]furan derivatives at room temperature in high yields (>90-95%) using nontoxic and inexpensive ion exchange resin Amberlyst-15. The notable advantages of the catalyst approach enables the reactions with high selectivity, short reactions time and excellent yields without generating any waste and was reused.

Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase

Selective inhibitors of human peptide deformylase (HsPDF) are predicted to constitute a new class of antitumor agents. We report the identification of benzofuran-4,5-diones as the first known selective HsPDF inhibitors and we describe their selectivity pr

BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS

The instant invention provides novel benzofuran-4,5-diones and pharmaceutical compositions thereof useful for inhibiting PDF and for treating proliferative and infectious diseases. Compounds may be selective for eukaryotic (e.g., human) PDF or prokaryotic PDF