172508-38-2Relevant academic research and scientific papers
Photochemistry of substituted propiophenones: An interesting α-and aryl substituents effect on their photobehaviour
Sonawane, Harikisan R.,Bellur, Nanjundiah S.,Nazeruddin
, p. 11281 - 11294 (2007/10/02)
Photochemistry of different α-substituted and phenyl-substituted propiophenones in methanol is investigated with a view to delineate the substituent effect with a special reference tu their rearrangement to α-arylpropanoic acids, an important class of nonsteroidal antiinflammatory agents. The results thus obtained bringsforth an important element of their reactivityprofile i.e. the α-chloro-substituent in combination with nuclear alkyl substituents (para>meta) favours 1,2-arylmigration leading to the synthetically useful reaction for α-arylpro panoic acids.
An efficient synthesis of fenoprofen, an important antiinflammatory agent
Sonawane, H. R.,Nanjundiah, B. S.,Nazeruddin, G. M.
, p. 705 - 706 (2007/10/02)
A simple and practical synthesis of (+/-)-fenoprofen, a well-known non-steroidal antiinflammatory agent, from the commercially available m-phenoxybenzaldehyde has been described.
