172534-88-2Relevant academic research and scientific papers
Synthesis of imidazole N-oxides in solvent-free conditions
Alcázar, Jesús,Begtrup, Mikael,De La Hoz, Antonio
, p. 1465 - 1470 (2007/10/03)
Cyclization of 1,2-diimines with oximes was performed under solvent-free conditions using silica gel and aluminum oxide as supports and catalysts. The reaction proceeded under milder reaction conditions to give imidazole N-oxides. The N-oxides were obtained in higher yields by easier work-up procedure than in the usual reactions performed in solution.
Synthesis of imidazole 1-oxides from 1,2-diimines
Alcazar, Jesus,Begtrup, Mikael,Hoz, Antonio de la
, p. 2467 - 2470 (2007/10/02)
Various 3-substituted imidazole 1-oxides have been prepared by reaction of a 1,2-dicarbonyl compound mono- or di-imine with an oxime.The structure of the oxime determines the imidazole C-2 substituent whilst the structure of the mono- or di-imine determines the substitution patterns at N-3, C-4 and C-5.
