3673-06-1

Usage

Uses

Used in Textile and Leather Manufacturing:
Glyoxal-bis-cyclohexylimine is used as a crosslinking agent in textile and leather manufacturing to improve the strength, durability, and resistance to environmental factors of the materials. Its ability to form stable complexes with proteins and nucleic acids enhances the quality and performance of the final products.
Used in Water Treatment:
In the water treatment industry, glyoxal-bis-cyclohexylimine is used as a biocide to control the growth of microorganisms, such as bacteria and fungi, that can cause contamination and deterioration of water quality. Its antimicrobial properties help maintain clean and safe water supplies.
Used in Pharmaceuticals:
Glyoxal-bis-cyclohexylimine is used in the pharmaceutical industry for its potential applications in drug development and delivery. Its ability to form stable complexes with proteins and nucleic acids can be utilized in the design of new drugs or drug delivery systems, enhancing their efficacy and safety.
Used in Material Preservation:
Glyoxal-bis-cyclohexylimine is used as a preservative in various industries to prevent the growth of microorganisms that can cause spoilage or degradation of materials. Its antimicrobial properties help extend the shelf life and maintain the quality of products.

Upstream product

• 108-91-8 cyclohexylamine 
• 141-46-8 Glycolaldehyde 
• 113832-57-8 N-ethylidenecyclohexylamine 
• 5459-93-8 N-ethyl-cyclohexanamine 
• 586-96-9 Nitrosobenzene 
• 4405-13-4 glyoxal trimer dihydrate 
• 131543-46-9 Glyoxal 
• 2280-44-6 D-Glucose 

Downstream Products

• 90959-16-3 1,4-Dicyclohexyl-2-methyl-1,4-dihydro-pyrazine 
• 139696-58-5 1,3-Dicyclohexyl-2-methoxy-2-methyl-2,3-dihydro-1H-[1,3,2]diazasilole 
• 172534-88-2 3-cyclohexylimidazole 1-oxide 
• 84349-14-4 2-chloro-3-(cyclohexylamino)naphthalene-1,4-dione 
• 1259518-25-6 C₁₄H₂₄Cl₂N₂Te 
• 1357266-06-8 diethyl 2,2'-dicyclohexyl-3,3'-bidiaziridine-1,1'-dicarboxylate 
• 1431142-86-7 1,3-dicyclohexyl-2-formylimidazolium perchlorate 
• 130473-69-7 (3aR,6aR)-1,4-Dicyclohexyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dithione 
• 88178-66-9 CoCl₂(c-Hex-DAB) 
• 566173-32-8 [PtCl₂{κ²N-(N,N'-bis(cyclohexyl)-ethylenediimine)₂}] 
• 1431142-90-3 1,3-dicyclohexylimidazolium perchlorate 

Relevant academic research and scientific papers

Cobalt(II) complexes of α-diimine derived from cycloalkylamines as controlling agents for organometallic mediated radical polymerization of vinyl acetate

A series of cobalt(II)-α-diimine complexes derived from cycloalkylamines (cycloalkyl = cyclopentyl (1a), cyclohexyl (1b), cycloheptyl (1c), and cyclooctyl (1d)) were synthesized: [CoCl2(Pent-DAB)] (2a), [CoCl2(Hex-DAB)] (2b), [CoCls

AZETIDINE DERIVATIVE

Disclosed in the present application are a compound represented by formula (I), or a pharmaceutically acceptable salt, a tautomer thereof, a stereoisomer thereof, or a geometrical isomer thereof, and uses thereof in the preparation of drugs for treating o

Ruthenium p-cymene complexes with α-diimine ligands as catalytic precursors for the transfer hydrogenation of ethyl levulinate to γ-valerolactone

The ruthenium compounds [(η6-p-cymene)RuCl{κ2N-(HCNR)2}]NO3 (R = 4-C6H4Me, [1]NO3; 4-C6H4OH, [2]NO3; C6H11═Cy, [3]NO3; 4-C6H10OH, [4]NO3; tBu, [5]NO3) were prepared in high yields from [(p-cymene)RuCl2]2, AgNO3 and the appropriate α-diimine. Compounds [2]PF6 and [4]PF6 were obtained by a straightforward reaction of [(η6-p-cymene)RuCl(MeCN)0.66]PF6, [6]PF6, with α-diimine, whereas [4]BPh4 was obtained by metathesis between [4]NO3 and NaBPh4. All the ruthenium products were characterized by analytical methods, IR, NMR and UV-Vis spectroscopy; in addition, the structure of [1]NO3 was ascertained by an X-ray diffraction study. Compounds [1-4]NO3, [4]PF6 and [4]BPh4 were investigated as catalytic precursors in the transfer hydrogenation reaction of ethyl levulinate to γ-valerolactone in isopropanol solution under microwave irradiation. [4]BPh4 was revealed to be the best catalytic precursor, affording γ-valerolactone in 62% yield under optimized experimental conditions.

Synthesis, Antitumor Activity, and Docking Study of 1,3-Disubstituted Imidazolium Derivatives

A series of 1,3-disubstituted imidazolium salts were synthesized through a convenient synthetic approach based on the reaction of 1,4-diazabuta-1,3-dienes with HClO4. Their antitumor activity was evaluated in vitro against a number of human cancer cells. 1,3-Bis[(3,5-bis(trifluoromethyl)phenyl]imidazolium perchlorate turned out to be the most active against A549 and MCF-7 cancer cell lines with IC50 values of 5.24 and 4.21 μM, respectively. The results of structure–activity relationship study indicated that substituents on the imidazole derivatives play an important role in their cytotoxic activities. Finally, molecular docking of some tested compounds was carried out in order to investigate their binding pattern with the CDK2.

Revelation from the Reaction of 1,4-Diazabutadiene with Perchloric Acid: An Approach to the Synthesis of Imidazolium Perchlorates

The reactions of 1,4-diazabutadienes 1 with HClO4were studied in detail. The final products obtained were not the hydroperchlorates of 1 but imidazolium perchlorates 2 or 3. A possible reaction process is postulated on the basis of the isolation of the intermediate 2-iminomethylimidazolium salt 4. The factors influencing the conversion of 4 to the imidazolium perchlorates 2 and 3 were discussed with regard to the electronic and steric effects of the N-substituents. This reaction can serve as an approach for the synthesis of imidazolium derivatives.

Heteroatom-substituted secondary phosphine oxides for Suzuki-Miyaura cross-coupling reactions

Several di-substituted diimines (3a–3f) and heteroatom-substituted unsaturated secondary phosphine oxides (HASPO, 6a–6f) were prepared and characterized. Compounds 6a–6f are regarded as pre-ligands because of their ability of tautomerization to heteroatom-substituted phosphinous acid (HAPA, 7a–7f). An unexpected 3e-coordinated palladium dibromide 8e was observed from the reaction of compound 6e with PdBr2. Molecular structures of pre-ligands 6a, 6c, and 6e, as well as palladium complexes 8e were determined by single crystal X-ray diffraction methods. When pre-ligand 6a was applied to palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, satisfactory yields were obtained. Density functional theory were employed to examine the electronic properties of HASPO 6a–6f pre-ligands, their corresponding 1,3-di-N-substituted tautomers 7a–7f, and the saturated counterpart 7as of 7a. Compound 7a is the most effective and genuine ligand in Suzuki-Miyaura reaction that is confirmed by its higher-lying lone-pair (LP) molecular orbital (HOMO-1). The LP orbital of 7c–7f is lower-lying HOMO-5. For each 7c–7f, two conformational rotamers with minute energy difference were located. Hirshfeld charge and population analysis of 7c–7f were also calculated in order to comprehend the electronic properties for these two rotamers for each HAPAs. Besides, the steric effect of HAPAs was estimated in terms of the Percent Buried Volume (%Vbur). This model has shown that 7a has similar steric property to that of PCy3, which is an effective ligand in Suzuki-coupling reactions.

METHOD OF PRODUCING ORGANIC SILICON COMPOUND

PROBLEM TO BE SOLVED: To provide a method of producing an organic silicon compound efficiently by improving a catalyst for hydrosilylation reactions of alkenes and alkynes. SOLUTION: An organic silicon compound can be produced efficiently by using an iron

Synthesis of bis-N-alkyl imidazolium salts and their palladium(0)(NHC) (η2-MA)2 complexes

New N-Alkyl-substituted imidazolium salts as well as a series of their corresponding [Pd(NHC)(MA)2] complexes have been obtained by three routes in good yield. The previously reported synthesis for the analogous N-aryl substituted [Pd(NHC)(MA)2] complexes has been improved. The N-alkyl-substituted [Pd(NHC)(MA)2] complexes are thermally more labile than their N-aryl counterparts. Catalytic transfer semi-hydrogenation of phenylpropyne resulted in good to excellent chemo- and stereo- selectivity conversion into (Z)-phenylpropene. The size of the alkyl substituents correlates with the rate of hydrogenation in the sense that more bulky substituents give rise to faster transfer hydrogenation rates. Copyright

Effect of ligand substituents in olefin polymerisation by half-sandwich titanium complexes containing monoanionic iminoimidazolidide ligands-MAO catalyst systems

Various half-sandwich titanium complexes containing iminoimidazolidide ligands, CpTiCl2[1,3-R2(CH2N)2CN] (1a-d) [R = Ph (a), 2,6-Me2C6H3 (b), cyclohexyl (c), tBu (d)], have been employed as the catalyst precursors for ethylene polymerisation, syndiospecific styrene polymerisation, and copolymerisation of ethylene with 1-hexene in the presence of MAO cocatalyst; 1d showed the highest catalytic activity for ethylene polymerisation whereas 1b showed the highest activity for syndiospecific styrene polymerisation.

Solving the clogging problem: Precipitate-forming reactions in flow

Solids go with the flow: A monodisperse flow in a microreactor provides an efficient method for keeping solid products away from channel walls. The use of a carrier phase, such as mineral oil, hexane, or toluene, enables solids to be synthesized without clogging of the reactor channels. Further injection points can be added to the microreactor to perform multistep syntheses (see picture). (Figure Presented)