172588-55-5

Basic information

• Product Name: (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-tert-butyl-2-oxo-cyclopentanecarboxylate
• CAS NO: 172588-55-5
• Molecular Weight: 579.801
• Mol File: 172588-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-tert-butyl-2-oxo-cyclopentanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-tert-butyl-2-oxo-cyclopentanecarboxylate(172588-55-5)
• EPA Substance Registry System: (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-tert-butyl-2-oxo-cyclopentanecarboxylate(172588-55-5)

Safety Data

• Hazardous Substances Data: 172588-55-5(Hazardous Substances Data)

Upstream product

• 448961-10-2 (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate 
• 87420-26-6 (1R,2S,3R)-3-[N-Phenylsulfonyl-N-(3,5-dimethylphenyl)amino]bornan-2-ol 
• 594-19-4 tert.-butyl lithium 
• 174757-25-6 5-Oxo-cyclopent-1-enecarboxylic acid (1R,2S,3R,4S)-3-[benzenesulfonyl-(3,5-dimethyl-phenyl)-amino]-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 

Relevant articles and documents

Enatiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates by conjugate addition of cuprates to asymmetry shielded 2-oxo-cyclopentenecarboxylates

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by transesterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Diastereoselective conjugate addition of equimolar amounts of mixed cuprates at -78°C and deprotection by ethanolysis gave enantiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates 13-18 and ent-13-18, valuable as chiral building blocks in natural product synthesis.