448961-10-2

Basic information

• Product Name: (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate
• Synonyms: (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate
• CAS NO: 448961-10-2
• Molecular Weight: 523.693
• Mol File: 448961-10-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate(448961-10-2)
• EPA Substance Registry System: (1R,2S,3R,4S)-<3--2-bornyl>-2-oxo-cyclopentane-carboxylate(448961-10-2)

Safety Data

• Hazardous Substances Data: 448961-10-2(Hazardous Substances Data)

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 87420-26-6 (1R,2S,3R)-3-[N-Phenylsulfonyl-N-(3,5-dimethylphenyl)amino]bornan-2-ol 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 

Downstream Products

• 174757-25-6 5-Oxo-cyclopent-1-enecarboxylic acid (1R,2S,3R,4S)-3-[benzenesulfonyl-(3,5-dimethyl-phenyl)-amino]-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 172588-54-4 (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-butyl-2-oxo-cyclopentanecarboxylate 
• 172588-55-5 (1R,2S,3R,4S)-<3--2-bornyl>-(1R,5S)-5-tert-butyl-2-oxo-cyclopentanecarboxylate 
• 448961-11-3 (2R,3S,1'R,2'S,3'R)-3-[N-benzenesulfonyl-N-(3,5-dimethylphenyl)-amino]-bornan-2'-yl 3-(3-furyl)-cyclopentan-1-one-2-carboxylate 

Relevant articles and documents

EPC synthesis of 5-substituted 2-oxo-cyclopentanecarboxylates via conjugate addition of cuprates to asymmetric shielded 2-oxo-cyclopentenecarboxylates

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by trans-esterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Dias

Enatiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates by conjugate addition of cuprates to asymmetry shielded 2-oxo-cyclopentenecarboxylates

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by transesterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Diastereoselective conjugate addition of equimolar amounts of mixed cuprates at -78°C and deprotection by ethanolysis gave enantiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates 13-18 and ent-13-18, valuable as chiral building blocks in natural product synthesis.