172608-30-9

Upstream product

• 26465-81-6 3,3-dimethylindan-1-one 
• 24273-36-7 (Z)-2-(hydroxyimino)-3,3-dimethyl-2,3-dihydro-1H-inden-1-one 
• 172608-23-0 rac-2-(acetoxyimino)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl acetate 
• 184583-22-0 (3aS,8bR)-3-((R)-2-Azido-3-phenyl-propionyl)-4,4-dimethyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 184583-21-9 (3aS,8bR)-3-((S)-2-Bromo-3-phenyl-propionyl)-4,4-dimethyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 184583-16-2 (3aS,8bR)-4,4-Dimethyl-3-(3-phenyl-propionyl)-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 100-39-0 benzyl bromide 
• 172608-27-4 (3aS,8bR)-4,4-Dimethyl-3-propionyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 

Downstream Products

• 184583-16-2 (3aS,8bR)-4,4-Dimethyl-3-(3-phenyl-propionyl)-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 184583-21-9 (3aS,8bR)-3-((S)-2-Bromo-3-phenyl-propionyl)-4,4-dimethyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 184583-22-0 (3aS,8bR)-3-((R)-2-Azido-3-phenyl-propionyl)-4,4-dimethyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 
• 14367-67-0 2-methyl-3-phenylpropionic acid 
• 172608-26-3 (3aS,8bR)-4,4-Dimethyl-3,3a,4,8b-tetrahydro-indeno[2,1-d]oxazol-2-one 

Relevant academic research and scientific papers

Design, synthesis, resolution, and application of a highly efficient chiral auxiliary: cis-2-amino-3,3-dimethyl-1-indanol

The chiral amino alcohol, cis-2-amino-3,3-dimethyl-1-indanol was synthesized and resolved. Its oxazolidinone derivative was found to be a highly efficient chiral auxiliary in diastereoselective alkylation, acylation, bromination, and hydroxylation reactions.

Design, Optical Resolution, and Application of Artificial Chiral Auxiliaries

Refering the structures of ephedrine and norephedrine, we successively designed artificial chiral auxiliaries, eryhtro-2-amino-1,2-diphenylethanol, cis-2-amino-1-acenaphthenol (S), and cis-2-amino-3,3-dimethyl- 1-indanol. Their racemic modifications could

Cis-2-amino-3,3-dimethyl-1-indanol: Synthesis, resolution, and application as a highly efficient chiral auxiliary

The chiral amino alcohol, cis-2-amino-3,3-dimethyl-1-indanol was synthesized and resolved. Its oxazolidinone derivative was found to be a highly efficient chiral auxiliary in an asymmetric alkylation reaction.