17271-13-5Relevant academic research and scientific papers
The halogenation of some benzamides takes place preferentially at the ortho,para positions
Dong, Chang-Zhi,Julia, Marc,Tang, Jie
, p. 1689 - 1696 (2007/10/03)
The orientation of chlorination and bromination of N,N-disubstituted benzamides in aqueous acetic acid is strongly influenced by the nature of the alkyl groups at the nitrogen atom. With large groups, the halogenation takes place fairly selectively at the ortho/para positions.
