172738-63-5Relevant academic research and scientific papers
SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE
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, (2008/06/13)
This invention provides a novel class of sulfonamide compounds of formula I which are aspartyl protease inhibitors: STR1 This invention also provides pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also provides methods for inhibition aspartyl protease activity and methods for treating viral infections using the compounds and compositions of this invention.
