172749-34-7

Upstream product

• 31139-36-3 dibenzyl dicarbonate 
• 172749-33-6 (3S,4R)-t-butyl azetidin-3-methyl-2-one-4-carboxylate 

Downstream Products

• 130931-65-6 (3R,4R)-3-amino-1-hydroxy-4-methylpyrrolidin-2-one 
• 172749-37-0 (2R,3S) 2-N-(benzyloxycarbonyl)-4-bromo-3-methylbutanoate 
• 172749-36-9 (2R,3S)-t-butyl 2-N-(benzyloxycarbonyl)-4-bromo-3-methylbutanoate 
• 172749-39-2 (3R,4R)-3-amino-3-N-(benzyloxycarbonyl)-1-benzyloxy-4-methylpyrrolidin-2-one 
• 172749-38-1 (2R,3S)-N-O-benzyl-2-N-(benzyloxycarbonyl)-4-bromo-3-methylbutanamide 
• 172749-41-6 (2R,3S)-t-butyl 2-N-(benzyloxycarbonyl)-3-methyl-4-(N-t-butoxycarbonyl-N-O-benzyl)butanoate 
• 172749-35-8 (2R,3S)-t-butyl 2-N-(benzyloxycarbonyl)-4-hydroxy-3-methylbutanoate 

Relevant academic research and scientific papers

Enantiospecific Synthesis of (3R,4R)-3-Amino-1-Hydroxy-4-Methyl Pyrrolidin-2-one (L-687,414), an NMDA Receptor Antagonist

An enantiospecific synthesis of the NMDA receptor antagonist (3R,4R)-3-amino-1-hydroxy-4-methylpyrrolidin-2-one via ring opening of the chiral β-lactam (9) is reported.