1728-18-3Relevant articles and documents
Cerium-free Luche reduction directed by rehydrated alumina
Jones-Mensah, Ebenezer,Nickerson, Leslie A.,Deobald, Jackson L.,Knox, Hailey J.,Ertel, Alyssa B.,Magolan, Jakob
, p. 3748 - 3753 (2016/06/06)
A 1,2-regioselective reduction of α,β-unsaturated ketones to their corresponding allylic alcohols is accomplished with NaBH4 in the presence of acidic activated alumina rehydrated to the Brockmann II grade by adding 3 % w/w water. The substrate scope includes eight ketones reduced in high regio- and diastereoselectivity to their corresponding allylic alcohols. This is the first example of the strategy of systematically tuning the surface chemistry of alumina via partial rehydration in order to modulate selectivity in a reaction. Alumina is an appealing alternative to the common Luche reduction additive, CeCl3, from the perspective of cost and procedural simplicity.
Thermodynamics of Vinyl Ethers. 31. Isomer Equilibria in Some Six- and Seven-Membered Cyclic Dienes
Taskinen, Esko,Nummelin, Kari
, p. 4844 - 4847 (2007/10/02)
The relative thermodynamic stabilities of 1,3-cyclohexadiene and 1,4-cyclohexadiene, together with a number of their alkoxy and other derivatives and some related seven-membered cyclic dienes, have been determined by chemical equilibration in Me2SO and cyclohexane solution at various temperatures.The values of the thermodynamic parameters ΣG, ΔH, and ΔS for the isomerization processes involved are discussed and show clearly that the apparently conjugated diene system of 1,3-cyclohexadiene is devoid of conjugation, contrary to that of 1,3-cycloheptadiene.
