172805-63-9Relevant academic research and scientific papers
Radical cyclization of thio- and seleno-esters - An intramolecular acylation approach
Kim, Sunggak,Jon, Sang Yong
, p. 1335 - 1336 (1996)
Both thio- and seleno-esters are utilized as carbonyl equivalent radical acceptors in radical cyclizations, where selenoesters are more efficient than thioesters due to the better leaving ability of the phenylseleno group.
5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE
-
Page/Page column 152, (2017/02/28)
Provided in some embodiments are compounds of Formula A, as defined herein, that modulate the activity of 5-HT2C receptor. Also provided in some embodiments are methods, such as, for weight management, inducing satiety, and decreasing food intake, and for
β elimination of a phosphonate group from an alkoxyl radical - Intramolecular acylation using acylphosphonate derivatives as carbonyl group acceptors
Cho, Chang Ho,Kim, Sunggak
, p. 917 - 921 (2007/10/03)
The possibility of β elimination of a phosphonate group in radical reactions was studied. The facile β elimination of the phosphonate group from an alkoxyl radical was observed for the first time, whereas the β elimination of the phosphonate group from an
β-elimination of a phosphonate group from an alkoxy radical: An intramolecular acylation approach using an acylphosphonate as a carbonyl group acceptor
Kim, Sunggak,Cho, Chang Ho,Lim, Chae Jo
, p. 9574 - 9575 (2007/10/03)
On the basis of facile β-elimination of a phosphonate group from an alkoxy radical, intramolecular acylation reaction has been developed, in which an acylphosphonate is used as an excellent carbonyl group radical acceptor. Copyright
3,4-Dehydro-2-hydroxy-6-(2-phenethyl)tetrahydropyran. 1,3-Acyclic diastereoselection in reaction with MeOH and its application in the synthesis of a racemic mevinolin analog
Yadav, Veejendra K.,Kapoor, Kamal K.
, p. 8 - 13 (2007/10/03)
3,4-Dehydro-2-hydroxy-6-(2-phenethyl)tetrahydropyran (6) and its dimer (7) both react with MeOH in the presence of a catalytic amount of conc. HCl to provide 2,4-bismethoxy-6-(2-phenylethyl)tetra-hydropyran with a decent level of 1,3-acyclic diastereoselection in favour of the 4,6-trans derivative (9a). The ratio of the arabino (9a) and xylo (9b) structures was an unprecedented 4:1. Models to account for the observed diastereoselectivity are discussed. Further transformation to the 2-oxo derivative and unmasking of the 4-OH function provide a rapid entry into a racemic mevinolin analog (14).
