17282-02-9

Usage

Chemical Properties

White solid

InChI:InChI=1/C6H6BrNO/c1-4-2-5(7)6(9)8-3-4/h2-3H,1H3,(H,8,9)

Upstream product

• 1003-68-5 5-methyl-2-pyridone 
• 1003-68-5 5-methyl-pyridin-2-ol 

Downstream Products

• 17282-03-0 3-bromo-2-chloro-5-methyl-pyridine 
• 1441005-66-8 C₁₉H₂₃BrN₂O₃ 
• 1206773-24-1 N-[4-[(E)-2-[3-tert-butyl-2-methoxy-5-(5-methyl-2-oxo-1H-pyridin-3-yl)phenyl]vinyl]phenyl]methanesulfonamide 
• 1160358-21-3 (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-methyl-7H-pyrazolo[3,4-b]pyridine 
• 1083168-84-6 2-methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 1613033-19-4 3-bromo-1-(3-(formyl)phenyl)-5-(methyl)-2(1H)-pyridinone 

Relevant academic research and scientific papers

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

3-Pyridinecarboxamide derivatives as HDL-cholesterol raising agents

The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.

Pyridine-3-carboxamide derivatives as CB1 inverse agonists

The present invention relates to compounds of the formula wherein X and R1 to R8 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors, such as obesity.

Novel Nucleophilic Substitution of Alkyl Bromo-2(1H)-pyridones

Nucleophilic substitution of certain alkyl bromo-2(1H)-pyridones gave some unexpected products where the alkyl group is substituted and the ring bromine is replaced by hydrogen.The expected ring substituted product is also formed, but only as the minor pr