17282-37-0

Basic information

• Product Name: 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE
• Synonyms: 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE;1-(4'-BROMOPHENACYL)PYRIDINIUM BROMIDE;1-(4-bromophenyl)-2-pyridin-1-ium-1-ylethanone,bromide
• CAS NO: 17282-37-0
• Molecular Formula: Br*C₁₃H₁₁BrNO
• Molecular Weight: 357.04054
• Mol File: 17282-37-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE(17282-37-0)
• EPA Substance Registry System: 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE(17282-37-0)

Safety Data

• Hazardous Substances Data: 17282-37-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE is used as a reagent or catalyst in organic synthesis for its ability to facilitate specific chemical reactions, enhancing the efficiency and selectivity of the processes involved.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE is utilized for the synthesis of various drugs. Its unique structure allows it to be a key component in the creation of new medicinal compounds, potentially leading to the development of novel treatments and therapies.
Used in Research Laboratories:
1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE is also employed in research laboratories for conducting a variety of chemical reactions. Its presence can help scientists explore new reaction pathways and mechanisms, contributing to the advancement of chemical knowledge and innovation.
Used in Chemical Research and Development:
1-(2-(4-BROMO-PHENYL)-2-OXO-ETHYL)-PYRIDINIUM, BROMIDE is used as a research tool in the development of new chemical processes and methodologies. Its unique properties can inspire the creation of innovative techniques and approaches in the field of chemistry.

InChI:InChI=1/C13H11BrNO/c14-12-6-4-11(5-7-12)13(16)10-15-8-2-1-3-9-15/h1-9H,10H2/q+1

Upstream product

• 110-86-1 pyridine 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 27762-29-4 (4-bromo-phenyl)-naphtho[2,1-d]oxazol-2-yl-methanone 
• 62953-33-7 4-benzo[1,3]dioxol-5-yl-2-(4-bromo-phenyl)-6-phenanthren-3-yl-pyridine 
• 27762-27-2 (4-bromo-phenyl)-naphtho[1,2-d]oxazol-2-yl-methanone 
• 78938-16-6 [6-(4-Bromo-benzoyl)-1,4-di-pyridin-3-yl-1,4-dihydro-[1,2,4,5]tetrazin-3-yl]-(4-bromo-phenyl)-methanone 
• 586-76-5 4-Bromobenzoic acid 
• 130837-09-1 2-(Bromophenyl)-9,10-anthraquinone 
• 130837-08-0 1-(4-Bromobenzoyl)-2-(4-bromophenyl)-9,10-anthraquinone 
• 130837-07-9 2-(4-Bromobenzoyl)-3-(4-bromobenzoylmethylene)-2,3-dihydronaphtho<1,2-b>furan-5(4H)-one 
• 33777-87-6 2,6-bis<4-bromophenyl>pyridine 
• 39183-93-2 2-p-Bromphenacyltropon 
• 39192-12-6 2-(1',2'-Di-p-brombenzoylaethyl)tropon 
• 40240-73-1 trans-1-(p-bromophenyl)-4-phenyl-2-butene-1,4-dione 

Relevant articles and documents

Diastereoselective synthesis of functionalised trans-tetrahydrobenzofuran-4-ones in an aqueous medium by using DABCO as an efficient catalyst

A one-pot, efficient synthesis of 11 novel 2,3-diacylated trans-tetrahydrobenzofuran-4-one derivatives has been achieved via a three-component condensation of a N-(4-halophenacyl)-pyridinium bromide, a cyclic 1,3-diketone such as 5,5-dimethyl-1,3-cyclohex

Cascade reactions of diazocarbonyl compounds with pyridinium aroylmethylides accompanied by water or benzoic acid elimination in the cyclocondensation step

The reaction of pyridinium aroylmethylides with diazocarbonyl compounds proceeds as a multistep process involving three ylide molecules and one diazo compound molecule. As a result, intermediate functionally substituted azines, if they contain carbonyl gr

Synthesis, characterization, and application of monodisperse poly L-Dopa microspheres

In this study, 3,4-dihydroxy-L-phenylalanine (L-Dopa) was solvothermally polymerized to monodisperse microspheres 1 μ m in diameter. Polymerization was carried out in dimethylformamide containing appropriate amounts of urea and L-Dopa at 120 ° C for 24 h.

1,2-Dicarbofunctionalization of Trifluoromethyl Alkenes with Pyridinium Salts via a Cycloaddition/Visible-Light-Enabled Fragmentation Cascade

Although trifluoromethyl alkenes have great synthetic potential, their 1,2-difunctionalization has been a challenge. In this Letter, we disclose the first 1,2-dicarbofunctionalization of trifluoromethyl alkenes with pyridinium salts via a cascade process

Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme

A series of 1,2,3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were screened for in?vitro whole-cell anti-tubercular activity against the susceptible H37Rv and multidrug-resistant (MDR) Mycobacterium tuberculosis (MTB) strains. Compounds 2b–2d, 3a

Silver-Promoted (4 + 1) Annulation of Isocyanoacetates with Alkylpyridinium Salts: Divergent Regioselective Synthesis of 1,2-Disubstituted Indolizines

An unprecedented silver-promoted regioselective (4 + 1) annulation of isocyanoacetates with pyridinium salts is reported. The established protocol provides controlled, facile, and modular access to a range of synthetically useful N-fused heterocyclic scaffolds containing indolizines, pyrrolo[1,2-a]quinolines, pyrrolo[2,1-a]isoquinolines, and 1H-imidazo[4,5-a]indolizin-2(3H)-ones. A mechanistic pathway involving nucleophilic addition/protonation/elimination/cycloisomerization is proposed.

Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors

A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhibitor

DMAP-Catalyzed Annulation Approach for Modular Assembly of Furan-Fused Chromenes

With a tandem DMAP-catalyzed reaction between o-AQM, in which it is generated in situ from propargylic amine, and acyl carbene surrogate (from pyridinium ylide), a variety of polyarylated chromenes are assembled in good yields. This process does not require transition-metal catalyst and exhibits easy manipulation of the arene group and good functional group compatibility, particularly the -Br group which can be further transformed to other functionalities by cross-coupling reactions. The modular feature of o-AQM substrates and the simple operation procedures add further advantages to this synthetic method.

Three-component synthesis of novel spirooxindole–furan derivatives using pyridinium salts

A simple and efficient synthesis of novel spirooxindole–furan derivatives has been investigated by a modified version of the“interrupted” Feist–Bénary (IFB) reaction of isatin derivatives, 1,3-dicarbonyl compounds and N-phenacyl pyridinium salts in the presence of triethylamine. The reaction has been carried out under mild conditions in ethanol, and the products were obtained in good to moderate yields with a simple work-up procedure.

Preparation method of 1-(4-bromophenyl)-2-pyridyl-1-yl-1-butanone bromide

The invention relates to a preparation method of 1-(4-bromophenyl)-2-pyridyl-1-yl-1-butanone bromide. The method comprises the following steps of dissolving acetophenone into a certain solvent; performing reaction with liquid bromine at -20 to 40 DEG C according to a certain proportion; preparing 2,4-dibromoacetophenone at 2 to 8 hours; in a certain solvent, performing reaction with a certain proportion of pyridine for 3 to 15 hours at 0 to 80 DEG C; after the reaction is completed, cooling the materials to the room temperature; performing ethyl acetate extraction, water and saturated salt solution washing, anhydrous sodium sulfate drying, rotary evaporation and concentration to obtain a coarse product of the 1-(4-bromophenyl)-2-pyridyl-1-yl-1-butanone bromide; recrystallizing the coarse product to obtain a pure product. The reaction raw materials can be easily obtained; the price is reasonable; the reaction conditions are mild; the operation is easy; the control is easy; the post treatment is simple; the product quality is stable; the purity is high.