172882-68-7Relevant academic research and scientific papers
BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF
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Page/Page column 61, (2012/08/28)
Disclosed herein are polybasic bacterial efflux pump inhibitors containing boronic acid functionality and theft methods of synthesis, methods of use, and pharmaceutical compositions. Some embodiments include methods of treating or preventing a bacterial infection by co-administering to a subject infected with bacteria or at risk of infection with bacteria the efflux pump inhibitor with another anti-bacterial agent
Potent human immunodeficiency virus type 1 protease inhibitors that utilize noncoded D-amino acids as P2/P3 ligands
Jungheim, Louis N.,Shepherd, Timothy A.,Baxter, Angela J.,Burgess, Jeffrey,Hatch, Steven D.,Lubbehusen, Penny,Wiskerchen, MaryAnn,Muesing, Mark A.
, p. 96 - 108 (2007/10/03)
Noncoded D-amino acids have been designed to replace the quinaldic amide- asparaginyl moiety (P2/P3 ligand) found in several potent human immunodeficiency virus (HIV) protease inhibitors such as LY289612. The substituted nitrogen, op
