825-83-2

Usage

InChI:InChI=1/C7H5F3S/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4,11H/p-1

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 109787-11-3 para-trifluoromethylbenzenesulphonic acid 
• 130782-68-2 S-(4-(trifluoromethyl)phenyl) N,N-dimethylcarbamothioate 
• 421-17-0 Trifluoromethylsulfenyl chloride 
• 108-95-2 phenol 
• 455-13-0 4-Iodobenzotrifluoride 
• 146397-87-7 p-(trifluoromethyl)phenyl trifluoromethanesulfonate 
• 98-56-6 4-chlorobenzotrifluoride 
• 2991-42-6 4-trifluorophenylsulfonyl chloride 
• 110-81-6 Diethyl disulfide 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 852-23-3 2-<4-Trifluormethyl-phenylmercapto-methyl>-benzoesaeure-aethylester 
• 131673-99-9 p-(trifluoromethyl)phenyl (trimethylsiloxy)methyl sulfide 
• 77795-46-1 <4-fluoro-2-(4-trifluoromethylphenylthio)phenyl>acetic acid 
• 136436-87-8 Dimethyl-[3-phenyl-3-(4-trifluoromethyl-phenylsulfanyl)-propyl]-amine 
• 64287-55-4 4-trifluormethylphenyl vinyl sulfide 
• 168910-84-7 2-Nitro-6-(4-trifluoromethyl-phenylsulfanyl)-benzonitrile 
• 172882-68-7 (S)-2-<(tert-butoxycarbonyl)amino>-3-<<(p-trifluoromethyl)phenyl>thio>propionic acid 
• 286377-47-7 3-methoxy-6-nitro-5-(4-trifluoromethyl-phenylsulfanyl)-benzofuran 
• 90141-51-8 1-(trifluoromethyl)-4-{[4-(trifluoromethyl)phenyl]sulfanyl}benzene 
• 1026940-66-8 3-chloro-5-(4-trifluoromethyl-phenylsulfanyl)-pyridine-4-carbaldehyde 
• 18715-45-2 4-trifluoromethylphenyl disulfide 
• 823219-98-3 5-(4-trifluoromethyl-phenylsulfanylmethyl)-isoxazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Palladium catalyzed synthesis of aryl thiols: Sodium thiosulfate as a cheap and nontoxic mercapto surrogate

A Pd-catalyzed coupling reaction of ArBr/ArCl/ArOTf with sodium thiosulfate takes place in presence of Cs2CO3 at 80 °C. The reaction mixture is directly treated with Zn/HCl to afford aryl thiols in good to excellent yields.

Copper-catalyzed coupling of thiourea with aryl iodides: The direct synthesis of aryl thiols

A general, economical and efficient protocol for the direct copper-catalyzed coupling of thiourea with aryl iodides is developed and it will be potentially applied in large-scale industry as a preferred process.

Thermal reactions of chloroarenes with hydrogen sulfide in the presence of methanol

Gas-phase reactions of chloroarenes (ClC6H4X, X = H, 4-CH3, 4-OH, 4-Cl, 4-CF3) with hydrogen sulfide or its precursors were investigated in the presence of methanol, which was a stronger H-donor than hydrogen sulfide. Introducing methanol increased the selectivity of arenethiols formation at X = H and 4-CH3 and did not affect the reaction selectivity at acceptor X. The efficiency of methanol influence was considered from the viewpoint of free-radical reaction mechanism and the stability of the arenethiyl radicals. 2005 Pleiades Publishing, Inc.

Direct synthesis of thioethers from sulfonyl chlorides and activated alcohols

An efficient, safe one-pot synthesis of thioethers from aromatic sulfonyl chlorides and activated alcohols has been developed under non-aqueous conditions.

ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS

The present invention relates to metal ion salts which can be used in electrolytes for producing electrochemical devices, including both primary and secondary batteries, photoelectrochemical cells and electrochromic displays. The salts have a low energy o

Molecular recognition in aqueous media. new binding studies provide further insights into the cation-π interaction and related phenomena

We describe a large number of binding studies in aqueous media designed to provide new insights into noncovalent binding interactions, especially the cation-π interaction. The studies include 7 different hosts, over 70 guests, and over 150 new binding constants. In addition to the now standard NMR methods, circular dichroism has proven to be an especially useful tool for determining aqueous binding constants. We have found that, in addition to the alkyliminium and tetraalkylammonium guests we have studied previously, sulfonium and guanidinium guests also show substantial cation-π effects. Bromination of the host greatly enhances its binding ability in a general fashion, primarily as a result of hydrophobic interactions. Addition of methoxy groups did not enhance binding, apparently as a result of a collapse of the host into a conformation that is not suitable for binding. Replacement of two benzene rings of the host by furans or thiophenes also did not enhance binding. Ab initio calculations provide a rationalization for this effect and suggest a clearer model for the cation-π interaction.

β-D-phenylthioxylosides, their method of preparation and their use as therapeutic agents

The present invention relates, by way of novel industrial products, to the β-D-phenylthioxyloside compounds of the formula STR1 in which: X represents a sulfur atom or an oxygen atom; R1, R2 and R3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group --CO--R (in which R represents a C1 -C4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH3), a C1 -C4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for R1 and R2, taken together, to form, with the phenyl group to which they are bonded, a β-naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeutic agents, especially as venous antithrombotics.

Thioether complexes of tungsten hexacarbonyl

The preparation of a series of organic and organometallic thioethers R3MSR' (M = C,Si,Ge, or Sn) is reported.From these, several new compounds of type 1 are synthesized, some of which contain para-substituted aryl functions for R and R'.In hexane solution in the carbonyl streching region of the ir the uv there is evidence for a degree of multiple bonding, at least in the M - S - WW - CO portion of these molecules.Multiple bonding extending into aromatic R or R'is small or non-existent and cannot be assessed precisely because of spontaneous decomposition of the complexes.All the complexes undergo a thermally initiated decomposition, the case of which depends on the nature of R, R', and M.The unusual W(I) thiolate cis-2 is the termal decomposition product.

HIGH-TEMPERATURE ORGANIC SYNTHESIS. XXVII. REACTIONS OF ALKANETHIONES WITH THE CHLORINE DERIVATIVES OF BENZENE, THIOPHENE, AND NAPHTHALENE

Alkanethiols react effectively with chlorobenzene, its derivatives, 1-chloronaphthalene, and 2-chlorothiophene at 600-660 deg C with the preferential formation of the corresponding aromatic or heteroatomic thiols.Ethanethiol is most reactive.When it is used instead of hydrogen sulfide in reactions with chlorobenzene or its 4-substituted derivatives, the yield of the aromatic thiols, from which the phenylthiyl radicals are generated with greater difficulty, increases more sharply than the yield of the thiophenols, which generate the more stable 4-XC6H4S radicals.The side products of the reactions are the corresponding diaryl sulfides, thiophene, benzothiophene, and toluene.

RESONANCE RAMAN SPECTRA OF RUBREDOXIN, DESULFOREDOXIN, AND THE SYNTHETIC ANALOGUE Fe(S2-o-xyl)2 - : CONFORMATIONAL EFFECTS.

The resonance Raman (RR) spectrum of the rubredoxin analogue Fe(S//2-o-xyl)//2** minus (S//2-o-xyl equals o-xylylene- alpha , alpha prime -dithiolate) shows four widely spaced bands (I-IV) in the Fe-S stretching region, 297, 321, 350, and 374 cm** minus *