172941-98-9

Upstream product

• 172941-95-6 [(R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-dodecanoylamino]-acetic acid ethyl ester 
• 172941-94-5 (R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-dodecanoic acid 
• 172941-77-4 Boc-L-Val-3(R)-aminododecanoic acid methyl ester 
• 2480-93-5 Boc-Orn(Z)-OH 
• 172941-96-7 valyl-((R)-3-nonyl-β-alanyl)-glycine-ethyl ester 

Downstream Products

• 172942-00-6 {(R)-3-[(S)-2-((S)-2-Amino-5-benzyloxycarbonylamino-pentanoylamino)-3-methyl-butyrylamino]-dodecanoylamino}-acetic acid 
• 172942-02-8 [3-((5S,8S,11R)-8-Isopropyl-11-nonyl-3,6,9,13-tetraoxo-1,4,7,10-tetraaza-cyclotridec-5-yl)-propyl]-carbamic acid benzyl ester 
• 172941-99-0 {(R)-3-[(S)-2-((S)-5-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-pentanoylamino)-3-methyl-butyrylamino]-dodecanoylamino}-acetic acid 

Relevant academic research and scientific papers

Synthesis and antifungal activity of rhodopeptin analogues. 1. Modification of the east and south amino acid moieties

(equation presented) East Amino Acid n=8, 10 South Amino Acid Synthetic Rhodopeptin Analogs Structure - activity relationships of the east and south amino acid modified analogues of rhodopeptins, novel antifungal cyclic tetrapeptides isolated from Rhodococcus species Mer-N1033, have been investigated. It was observed that a basic amino acid moiety (lysine or ornithine) as the east amino acid and a hydrophobic and bulky neutral amino acid (i.e., γ-methylleucine) as the south amino acid were indispensable structure motifs for antifungal activity of rhodopeptin analogues.