172974-14-0Relevant articles and documents
Optimization of Alkylating Agent Prodrugs Derived from Phenol and Aniline Mustards: A New Clinical Candidate Prodrug (ZD2767) for Antibody-Directed Enzyme Prodrug Therapy (ADEPT)
Springer, Caroline J.,Dowell, Robert,Burke, Philip J.,Hadley, Elma,Davies, D. Huw,et al.
, p. 5051 - 5065 (2007/10/03)
Sixteen novel potential prodrugs derived from phenol or aniline mustards and their 16 corresponding drugs with ring substitution and/or different alkylating functionalities were designed.The 4-bis(2-bromoethyl)-(1a), 4-bis(2-iodoethyl)-(1b), and