172983-78-7

Basic information

• Product Name: 3-(4-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-indol-3-ol
• Synonyms: 3-(4-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-indol-3-ol
• CAS NO: 172983-78-7
• Molecular Weight: 243.281
• Mol File: 172983-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-indol-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-indol-3-ol(172983-78-7)
• EPA Substance Registry System: 3-(4-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-indol-3-ol(172983-78-7)

Safety Data

• Hazardous Substances Data: 172983-78-7(Hazardous Substances Data)

Upstream product

• 172984-02-0 N-(2-iodoanilinomethyl)succinimide 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 57056-93-6 N-methyl-2-iodoaniline 
• 172983-96-9 1-(4-Fluoro-phenyl)-2-[(2-iodo-phenyl)-methyl-amino]-ethanone 

Downstream Products

• 93957-59-6 3-(4-fluorophenyl)-1-methyl-1H-indole 

Relevant articles and documents

A NEW SYNTHESIS OF 3-SUBSTITUTED INDOLINES AND INDOLES

3-Phenyl- and 3-alkyl-3-hydroxyindolines were synthesized by intramolecular Barbier reaction of phenyl and alkyl N-(2-iodophenyl)-N-methylaminomethyl ketones with n-BuLi, which were easily prepared from N-methyl-2-iodoaniline and bromomethyl ketones.The treatment of the indolines with acid gave the corresponding indoles in quantitative yields.