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2,8-Dichloro-10H-phenothiazine is a chemical compound with the molecular formula C12H8Cl2N2S. It is a derivative of phenothiazine, a heterocyclic compound consisting of a tricyclic structure with a sulfur atom and two nitrogen atoms. This particular compound is characterized by the presence of two chlorine atoms attached to the 2nd and 8th carbon positions of the phenothiazine ring. 2,8-Dichloro-10H-phenothiazine is often used as an intermediate in the synthesis of various pharmaceuticals, dyes, and agrochemicals due to its versatile chemical properties. It is typically synthesized through the chlorination of phenothiazine using chlorine gas or other chlorinating agents. The compound is known for its stability and reactivity, making it a valuable building block in the chemical industry.

1730-45-6

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1730-45-6 Usage

Chemical class

Phenothiazine

Structure

Presence of two chlorine atoms at positions 2 and 8 on the phenothiazine ring

Biological activities

Antipsychotic, anti-inflammatory, and antihistaminic properties

Potential uses

Pharmaceutical industry, antifungal agent, precursor for other organic compounds

Industrial applications

Synthesis of various pharmaceuticals and agrochemicals

Safety

Handle with care due to potential hazards

Check Digit Verification of cas no

The CAS Registry Mumber 1730-45-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,3 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1730-45:
(6*1)+(5*7)+(4*3)+(3*0)+(2*4)+(1*5)=66
66 % 10 = 6
So 1730-45-6 is a valid CAS Registry Number.

1730-45-6Downstream Products

1730-45-6Relevant academic research and scientific papers

Synthesizing method of phenothiazine compound serving as medical intermediate

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Paragraph 0054; 0055; 0056-0058; 0060; 0061; 0065-0066, (2017/08/25)

The invention relates to a synthesizing method of a phenothiazine compound which can serve as a medical intermediate and is shown as the formula (III) (please see the formula in the description). The method comprises the steps that at room temperature, a compound shown as the formula (I) (please see the formula in the description), a compound shown as the formula (II) (please see the formula in the description), a catalyst, a ligand, alkali and auxiliaries are added into an organic solvent, the temperature is increased to 70 DEG C to 90 DEG C, reacting under stirring is conducted for 7 hours to 10 hours, aftertreatment is conducted after reacting is finished, and then the compound shown as the formula (III) is obtained, wherein R1 and R2 are selected from H, C1-C6 alkyl groups, C1-C6 alkoxy groups and halogen separately, and X is halogen. According to the method, through usage of the appropriate reactants and comprehensive selection and synergistic promotion of the catalyst, the ligand, the alkali, the auxiliaries and the organic solvent, the target product can be obtained at a high yield, and a good application prospect and the industrialized production potential are achieved.

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