922552-53-2 Usage
Uses
Used in Pharmaceutical Synthesis:
(2-bromo-5-chlorophenyl)hydrazine is used as a reactant/reagent in the synthetic preparation of tryptamine derivatives. Its unique structure allows for the formation of these biologically active compounds, which have potential applications in medicine.
Used in Organic Synthesis:
The bromine atom in (2-bromo-5-chlorophenyl)hydrazine can be employed as a protecting group during organic synthesis. This feature is particularly useful in the synthesis of complex organic molecules, where selective protection and deprotection of functional groups are necessary.
Used in Antiviral Drug Development:
(2-bromo-5-chlorophenyl)hydrazine is also used for the preparation of amides of amino acids and their analogs, which have potential antiviral properties. The presence of the halogenated phenyl ring may contribute to the antiviral activity of these compounds, making them valuable candidates for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 922552-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,2,5,5 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 922552-53:
(8*9)+(7*2)+(6*2)+(5*5)+(4*5)+(3*2)+(2*5)+(1*3)=162
162 % 10 = 2
So 922552-53-2 is a valid CAS Registry Number.
922552-53-2Relevant academic research and scientific papers
Syntheses of 4-, 5-, 6-, and 7-substituted tryptamine derivatives and the use of a bromine atom as a protecting group
René, Olivier,Fauber, Benjamin P.
supporting information, p. 830 - 833 (2014/02/14)
Orthogonal syntheses of 4-, 5-, 6-, and 7-chloro substituted tryptamine derivatives were performed under the Grandberg-Zuyanova-modified Fisher indole-synthesis conditions. In the 4- and 6-substituted tryptamine cases, a bromine atom was utilized as an easily cleavable protecting group, which allowed complete regiocontrol. In addition, a chlorine substituent was preserved in the debromination step and could be utilized as a synthetic handle for late-stage diversification under modern Pd(0) catalysis conditions.
1, 5-DIHYDRO-PYRAZOLO (3, 4-D) PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A MODULATORS FOR THE TEATMENT OF CNS DISORDERS
-
Page/Page column 57, (2009/07/03)
The invention relates to novel substituted pyrazolopyrimidines. Chemically, the compounds are characterised by general Formula (I): with R1 being phenyl or pyridyl, any of which is substituted with 1 to 4, preferably 1 to 3 substituents X; X in
