173034-30-5Relevant academic research and scientific papers
Aromatization reactions of 2-cyclohexenones and 1,3-cyclohexadien-1-amines with iodine/sodium alkoxide
Hegde, Shridhar G.,Kassim, Amude M.,Kennedy, April I.
, p. 1689 - 1698 (2001)
2-Cyclohexenones containing an electron withdrawing group in the 4-position and the corresponding N-alkyl-1,3-cyclohexadien-1-amines undergo regioselective iodination and aromatization to give 2-iodophenols and N-alkyl-2-iodoanilines, respectively, upon reaction with iodine and sodium alkoxide. By contrast, N,N-dialkyl-1,3-cyclohexadien-1-amine derivatives undergo non-iodinative aromatization to simple N,N-dialkylanilines under similar conditions.
Aromatization of Cyclohexenones with Iodine/sodium alkoxide. A Regioselective synthesis of 2-Iodophenols
Hegde, Shridhar G.,Kassim, Amude M.,Ingrum, April I.
, p. 8395 - 8398 (2007/10/02)
Aromatizations of a wide variety of easily accessible 2-cyclohexenone-4-carboxylates with iodine and sodium ethoxide give the corresponding 2-iodophenols in good yield and high regioselectivity.
