173088-58-9Relevant academic research and scientific papers
New water-soluble duocarmycin derivatives: Synthesis and antitumor activity of A-ring pyrrole compounds bearing β-heteroarylacryloyl groups
Amishiro, Nobuyoshi,Nagamura, Satoru,Kobayashi, Eiji,Gomi, Katsushige,Saito, Hiromitsu
, p. 669 - 676 (2007/10/03)
A series of A-ring pyrrole compounds of duocarmycin bearing 4'-methoxy- β-heteroarylacryloyl groups were synthesized and evaluated for in vitro anticellular activity against HeLa S3 cells and in vivo antitumor activity against murine sarcoma 18
