173091-90-2

Upstream product

• 136159-65-4 (S)-4-benzyl-3-(3-phenylpropanoyl)oxazolidin-2-one 
• 173091-89-9 C₆₀H₇₉N₃O₁₀Si 
• 173092-01-8 (S)-4-[(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-ethyl]-2-isobutyl-2-(3-methyl-but-2-enyl)-3-oxo-2,3-dihydro-pyrrole-1-carboxylic acid allyl ester 
• 173091-86-6 {(S)-4-[(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-ethyl]-2-isobutyl-3-oxo-2,3-dihydro-1H-pyrrol-2-yl}-acetaldehyde 
• 178032-88-7 (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one 
• 173092-04-1 ((S)-2-Benzyl-5-methyl-hex-4-enyloxy)-tert-butyl-dimethyl-silane 
• 645-45-4 hydrocinnamic acid chloride 
• 173092-00-7 (S)-2-benzyl-5-methyl-hex-4-en-1-ol 
• 173092-05-2 C₃₆H₄₈N₂O₇ 
• 173092-08-5 (4S,5S)-5-((S)-2-Allyloxycarbonylamino-2-methoxycarbonyl-3-phenyl-propyl)-4-benzyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 160978-16-5 (2R,4S)-4-Benzyl-4-((2S,3S)-3-tert-butoxycarbonylamino-2-hydroxy-4-phenyl-butyl)-2-tert-butyl-5-oxo-oxazolidine-3-carboxylic acid allyl ester 
• 173240-65-8 (4S,5S)-5-((S)-2-Amino-2-methoxycarbonyl-3-phenyl-propyl)-4-benzyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 173091-87-7 (R)-3-Benzyl-4-(tert-butyl-dimethyl-silanyloxy)-butyraldehyde 
• 147240-29-7 (2R,4R)-4-Benzyl-2-tert-butyl-5-oxo-oxazolidine-3-carboxylic acid allyl ester 

Downstream Products

• 173091-98-0 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 
• 173091-92-4 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionamide 
• 173091-95-7 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-N-tert-butyl-3-phenyl-propionamide 
• 173240-66-9 {(1S,2S)-1-Benzyl-3-[(2S,5'S)-5'-benzyl-4-((R)-1-carbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-yl]-2-hydroxy-propyl}-carbamic acid (S)-(tetrahydro-furan-3-yl) ester 
• 173091-94-6 (R)-2-((2S,5'S)-5'-Benzyl-5'-{(2S,3S)-2-hydroxy-4-phenyl-3-[(S)-(tetrahydro-furan-3-yl)oxycarbonylamino]-butyl}-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl)-3-phenyl-propionic acid methyl ester 
• 173091-91-3 (4S,5S)-4-Benzyl-5-[(2S,5'S)-5'-benzyl-4-((R)-1-carbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 173091-97-9 {(1S,2S)-1-Benzyl-3-[(2S,5'S)-5'-benzyl-4-((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-yl]-2-hydroxy-propyl}-carbamic acid (S)-(tetrahydro-furan-3-yl) ester 
• 173092-09-6 (4S,5S)-4-Benzyl-5-[(2S,5'S)-5'-benzyl-4-((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Pyrrolinone-based HIV protease inhibitors. Design, synthesis, and antiviral activity: Evidence for improved transport

Pyrrolinone-based peptidomimetics, the first mimics of β-strands, are potent inhibitors of HIV-1 protease. Importantly, the bis(pyrrolinones) described herein proved to be more active in cellular antiviral assays compared with an analogous peptide-derived