178032-88-7

Basic information

• Product Name: (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one
• Synonyms: (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one
• CAS NO: 178032-88-7
• Molecular Weight: 377.483
• Mol File: 178032-88-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one(178032-88-7)
• EPA Substance Registry System: (S)-4-Benzyl-3-((S)-2-benzyl-5-methyl-hex-4-enoyl)-oxazolidin-2-one(178032-88-7)

Safety Data

• Hazardous Substances Data: 178032-88-7(Hazardous Substances Data)

Upstream product

• 645-45-4 hydrocinnamic acid chloride 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 

Downstream Products

• 173091-89-9 C₆₀H₇₉N₃O₁₀Si 
• 173092-02-9 (2S,5'S)-5'-Benzyl-5'-((4S,5S)-4-benzyl-3-tert-butoxycarbonyl-2,2-dimethyl-oxazolidin-5-ylmethyl)-4-((R)-1-carboxy-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid diallyl ester 
• 173092-09-6 (4S,5S)-4-Benzyl-5-[(2S,5'S)-5'-benzyl-4-((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 173091-97-9 {(1S,2S)-1-Benzyl-3-[(2S,5'S)-5'-benzyl-4-((R)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-yl]-2-hydroxy-propyl}-carbamic acid (S)-(tetrahydro-furan-3-yl) ester 
• 173091-91-3 (4S,5S)-4-Benzyl-5-[(2S,5'S)-5'-benzyl-4-((R)-1-carbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 173091-90-2 (4S,5S)-4-Benzyl-5-[(2S,5'S)-5'-benzyl-4-((R)-1-carboxy-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 173091-94-6 (R)-2-((2S,5'S)-5'-Benzyl-5'-{(2S,3S)-2-hydroxy-4-phenyl-3-[(S)-(tetrahydro-furan-3-yl)oxycarbonylamino]-butyl}-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl)-3-phenyl-propionic acid methyl ester 
• 173240-66-9 {(1S,2S)-1-Benzyl-3-[(2S,5'S)-5'-benzyl-4-((R)-1-carbamoyl-2-phenyl-ethyl)-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-5'-yl]-2-hydroxy-propyl}-carbamic acid (S)-(tetrahydro-furan-3-yl) ester 
• 173091-95-7 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-N-tert-butyl-3-phenyl-propionamide 
• 173091-92-4 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionamide 
• 173091-98-0 (R)-2-[(2S,5'S)-5'-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-5'-benzyl-2-isobutyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 
• 173092-01-8 (S)-4-[(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-ethyl]-2-isobutyl-2-(3-methyl-but-2-enyl)-3-oxo-2,3-dihydro-pyrrole-1-carboxylic acid allyl ester 
• 173091-86-6 {(S)-4-[(R)-1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-phenyl-ethyl]-2-isobutyl-3-oxo-2,3-dihydro-1H-pyrrol-2-yl}-acetaldehyde 
• 173092-04-1 ((S)-2-Benzyl-5-methyl-hex-4-enyloxy)-tert-butyl-dimethyl-silane 

Relevant articles and documents

Pyrrolinone-based HIV protease inhibitors. Design, synthesis, and antiviral activity: Evidence for improved transport

Pyrrolinone-based peptidomimetics, the first mimics of β-strands, are potent inhibitors of HIV-1 protease. Importantly, the bis(pyrrolinones) described herein proved to be more active in cellular antiviral assays compared with an analogous peptide-derived