17312-31-1

Basic information

• Product Name: INOPHYLLUM-E
• Synonyms: INOPHYLLUM-E;(+)-Inophyllolide;Inophyllolide
• CAS NO: 17312-31-1
• Molecular Formula: C₂₅H₂₂O₅
• Molecular Weight: 402.44
• Mol File: 17312-31-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 186-188 °C
• Boiling Point: 608.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.245±0.06 g/cm3(Predicted)
• CAS DataBase Reference: INOPHYLLUM-E(CAS DataBase Reference)
• NIST Chemistry Reference: INOPHYLLUM-E(17312-31-1)
• EPA Substance Registry System: INOPHYLLUM-E(17312-31-1)

Safety Data

• Hazardous Substances Data: 17312-31-1(Hazardous Substances Data)

Upstream product

• 5302-74-9 mammea A/BB cyclo D 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 685844-45-5 (8R,9R)-5-Hydroxy-8,9-dimethyl-4-phenyl-8,9-dihydro-pyrano[2,3-f]chromene-2,10-dione 
• 685844-48-8 (8R,9S)-5-Hydroxy-8,9-dimethyl-4-phenyl-8,9-dihydro-pyrano[2,3-f]chromene-2,10-dione 
• 172805-13-9 6-(2-Bromo-2-methylbutanoyl)-5-methoxy-2,2-dimethyl-10-phenyl-2H,8H-benzo<1,2-b:3,4-b'>dipyran-8-one 
• 161633-70-1 5-Methoxy-2,2-dimethyl-6-(2-methylbutanoyl)-10-phenyl-2H,8H-benzo<1,2-b:3,4-b'>dipyran-8-one 
• 548-27-6 calophyllolide 
• 98192-65-5 5,7-Dihydroxy-8-(2-methylbutanoyl)-4-phenyl-2H-chromen-2-one 
• 31525-67-4 dimethylacetal of 3-methyl-3-hydroxybutyraldehyde 
• 172805-18-4 5-Hydroxy-2,2-dimethyl-6-<(E)-2-methylbut-2-enoyl>-10-phenyl-2H,8H-benzo<1,2-b:3,4-b'>dipyran-8-one 
• 628-13-7 pyridine hydrochloride 
• 680575-77-3 (8R,9S)-8,9-dihydro-8,9-dimethyl-5-methoxy-4-phenyl-2H,10H-benzo[1,2-b;5,6-b']dipyran-2,10-dione 
• 41135-07-3 (+)-cis-dihydroinophyllolide 

Downstream Products

• 41135-08-4 (10R,11S,12R)-12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-dihydro-6H,10H-dipyrano[2,3-f;2',3'-h]chromen-2-one 
• 41135-08-4 (+/-)-Inophyllum B 
• 41135-07-3 (+)-cis-dihydroinophyllolide 
• 41135-08-4 NC 127858 
• 477-23-6 (+/-)-3c-(5-hydroxy-2r,3t,8,8-tetramethyl-4-oxo-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-6-yl)-3t-phenyl-acrylic acid 
• 121968-71-6 (+/-)-3c-(5-methoxy-2r,3t,8,8-tetramethyl-4-oxo-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-6-yl)-3t-phenyl-acrylic acid methyl ester 

Relevant articles and documents

Concise Synthesis of Anti-HIV-1 Active (+)-Inophyllum B and (+)-Calanolide A by Application of (-)-Quinine-Catalyzed Intramolecular Oxo-Michael Addition

(-)-Quinine-catalyzed intramolecular oxo-Michael addition (IMA) of 7-hydroxy-5-methoxy-8-tigloylcoumarins was developed for the enantioselective construction of 2,3-dimethyl-4-chromanone systems in the context of the asymmetric synthesis of anti-HIV-1 act

Synthesis of the calophyllum coumarins

Synthetic routes leading to the synthesis of the natural 4-alkyl and 4- phenyl coumarins isolated from Calophyllum sp. are reported. The reported structures of calanolides C and D and oblongutide are incorrect and have been corrected by unambiguous synthesis.