31525-67-4

Basic information

• Product Name: 4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97
• Synonyms: 4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97;β-hydroxyisovaleraldehyde dimethyl acetal;4,4-Dimethoxy-2-methylbutan-2-ol;4,4-Dimethoxy-2-methyl-2-butanol 97%
• CAS NO: 31525-67-4
• Molecular Formula: C₇H₁₆O₃
• Molecular Weight: 148.2
• Mol File: 31525-67-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 206.4°Cat760mmHg
• Flash Point: 158 °F
• Appearance: /
• Density: 0.956 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0562mmHg at 25°C
• Refractive Index: n20/D 1.4226(lit.)
• PKA: 15.19±0.29(Predicted)
• CAS DataBase Reference: 4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97(31525-67-4)
• EPA Substance Registry System: 4 4-DIMETHOXY-2-METHYL-2-BUTANOL 97(31525-67-4)

Safety Data

• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 31525-67-4(Hazardous Substances Data)

Usage

Uses

4,4-Dimethoxy-2-methyl-2-butanol may be used in the microwave-mediated synthesis of 2,2-dimethyl-2H-chromones. It may also be used in the preparation of alkyl substituted 3′R,4′R-di-O-(-)-camphanoyl-2′,2′-dimethyldihydropyrano[2,3-f]chromone (DCP) analogs.

General Description

4,4-Dimethoxy-2-methyl-2-butanol is an organic building block.

InChI:InChI=1/C7H16O3/c1-7(2,8)5-6(9-3)10-4/h6,8H,5H2,1-4H3

Upstream product

• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 75-16-1 methylmagnesium bromide 
• 917-64-6 methyl magnesium iodide 
• 74-88-4 methyl iodide 

Downstream Products

• 57601-61-3 6,6,10,10-tetramethyl-2H,6H,10H-benzo<1,2-b:13,4-b':5,6-b''>tripyran-2-one 
• 31525-75-4 5-hydroxy-8,8-dimethyl-2H,8H-benzo<1,2-b:3,4-b'>dipyran-2-one 
• 106726-12-9 5-hydroxy-10,10-dimethyl-2H,8H-benzo<1,2-b:3,4-b'>dipyran-2-one 
• 34187-25-2 candidine 
• 34187-26-3 5-hydroxy-6'',6''-dimethylpyrano<3'',2'':6,7>flavone 
• 54287-99-9 5-hydroxy-2,2-dimethyl-2H-chromene-6-carbaldehyde 
• 31525-76-5 5-methoxyseselin 
• 64125-33-3 5-methoxy-8,8-dimethyl-2-phenyl-4H,8H-benzo[1,2-b:3,4-b’]dipyran-4-one 
• 74517-64-9 5-Methoxy-2,2-dimethyl-8-phenyl-2H,6H-benzo<1,2-b : 5,4-b'>dipyran-6-one 
• 89482-13-3 5-acetoxy-6'',6''-dimethylpyrano<2'',3'':7,8>flavone 
• 89482-14-4 5-acetoxy-6'',6''-dimethylpyrano<3'',2'':6,7>flavone 
• 87963-59-5 6-formyl-5-hydroxy-2,2-dimethyl-3-phenylthiochroman 
• 91078-11-4 5-Methoxymethoxy-2,2-dimethyl-3-phenylsulfanyl-chroman-6-carbaldehyde 
• 111492-45-6 3-(5-methoxymethoxy-2,2-dimethyl-2H-benzopyran-6-yl)-1-(2-hydroxy-4-methoxymethoxyphenyl)prop-2-en-1-one 

Relevant articles and documents

Asymmetric Solid-Phase Synthesis of (3′R,4′R)-Di-O-cis-acyl 3-Carboxyl Khellactones

Matrix Presented We describe a practical parallel synthesis of (3′R,4′R)-di-O-cis-acyl 3-carboxyl khellactones on a solid phase in high yield. The highlights of this synthesis include a Knoevenagel condensation, asymmetric dihydroxylation, catalyzed acylation, and product cleavage from the solid support.

Fructose 1,6-Diphosphate Aldolase Catalyzed Stereoselective Synthesis of C-Alkyl and N-Containing Sugars: Thermodynamically Controlled C-C Bond Formations.

Fructose 1,6-diphosphate aldolase catalyzed aldol condensations have been used in syntheses of several new N-containing and C-alkyl sugars on 4-20 mmol scales.The enzyme is highly specific for dihydroxyacetone phosphate as donor but accepts a number of achiral and chiral aldehydes (both D and L isomers) as acceptors.Due to the reversible nature of the aldol reaction, a thermodynamically controlled approach was employed for the syntheses in which racemic aldehydes were used as substrates and thermodynamically more stable products were preferentially produced.