173154-01-3

Basic information

• Product Name: (4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone
• Synonyms: (4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone;2-Oxazolidinone, 3-[4-azido-2-(1-Methylethyl)-1-oxo-4-[tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-, [2S-[2[1(R*),2R*,4R*],4]]-;3-[4-azido-2-(1-Methylethyl)-1-oxo-4-[tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-, [2S-[2[1(R*),2R*,4R*],4]]-2-oxazolidinone;(4S)-3-[(2S,4S)-4-azido-2-isopropyl-4-[(2S,4S)-4-isopropyl-5-oxo-tetrahydrofuran-2-yl]butanoyl]-4-benzyl-oxazolidin-2-one;(4S)-3-[(2S,4S)-4-azido-4-[(2S,4S)-5-oxo-4-propan-2-yloxolan-2-yl]-2-propan-2-ylbutanoyl]-4-benzyl-1,3-oxazolidin-2-one
• CAS NO: 173154-01-3
• Molecular Formula: C₂₄H₃₂N₄O₅
• Molecular Weight: 457
• EINECS: 1312995-182-4
• Mol File: 173154-01-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 105℃
• Appearance: /
• CAS DataBase Reference: (4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone(173154-01-3)
• EPA Substance Registry System: (4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone(173154-01-3)

Safety Data

• Hazardous Substances Data: 173154-01-3(Hazardous Substances Data)

Usage

General Description

"(4S)-3-[(2S,4S)-4-Azido-2-(1-Methylethyl)-1-oxo-4-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]butyl]-4-(phenylMethyl)-2-Oxazolidinone" is a complex chemical compound. Its specificity is derived from its molecular structure, consisting of a 4-azido group, oxazolidinone, furanyl moieties, and phenylmethyl portion. The compound possesses various functional groups like azido, oxo, and methyl, hinting at its potential for diverse reactions. The "S" in its chemical name indicates the configuration of the chiral centers in the molecule, suggesting it may occur in multiple stereoisomeric forms. Its extensive structure implies a highly specific synthesis process and its uses may be specialized, possibly within certain chemical or pharmaceutical applications. Its exact properties, reactivity and applications would have to be explored further through dedicated research.

InChI:InChI=1/C24H32N4O5/c1-14(2)18(11-20(26-27-25)21-12-19(15(3)4)23(30)33-21)22(29)28-17(13-32-24(28)31)10-16-8-6-5-7-9-16/h5-9,14-15,17-21H,10-13H2,1-4H3/t17-,18-,19-,20-,21-/m0/s1

Upstream product

• 173154-00-2 (S)-4-benzyl-3-((2S,4R)-4-bromo-2-isopropyl-4-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-butanoyl)oxazolidin-2-one 
• 145589-03-3 (S)-4-benzyl-3-(3-methylbutanoyl)oxazolidin-2-one 
• 108-12-3 isopentanoyl chloride 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 7732-18-5 water 
• 993-22-6 tetrabutylammoniun azide 

Downstream Products

• 1257529-92-2 (3S,5S)-5-((1S,3S)-1-Azido-3-(hydroxy(4-methoxy-3-(3-methoxypropoxy)phenyl)methyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one 
• 173154-02-4 (2S,4S)-4-azido-2-isopropyl-4-[(2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl]butanal 
• 173154-03-5 (3S,5S)-5-[(1S,3S)-1-azido-3-(hydroxymethyl)-4-methylpentyl]-3-isopropyldihydrofuran-2(3H)-one 
• 934841-30-2 (3S,5S)-3-isopropyl-5-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)pyrrolidin-2-one 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 

Relevant articles and documents

1,8-dioxo -4,5-epoxy composition and method of making the same

The invention relates to 1,8-dicarbonyl-4,5-epoxy compound and a preparation method thereof. The structure formula of the 1,8-dicarbonyl-4,5-epoxy compound is shown in the formula I, and the compound I is further opened and closed by azide substitution. A critical midbody azide lactone compound of aliskiren can be obtained at high selectivity and high yield.

METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES

Disclosed are methods for treating Alzheimer’s disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula 1 (1) wherein the variables R1-R8 and X are defined herein.