173158-99-1Relevant articles and documents
A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 1. Construction of the basic framework
Abe, Yoshito,Kayakiri, Hiroshi,Satoh, Shigeki,Inoue, Takayuki,Sawada, Yuki,Imai, Keisuke,Inamura, Noriaki,Asano, Masayuki,Hatori, Chie,Katayama, Akira,Oku, Teruo,Tanaka, Hirokazu
, p. 564 - 578 (2007/10/03)
A novel class of potent, selective, and orally active non-peptide bradykinin (BK) B2 receptor antagonists were designed and synthesized starting from 8-benzyloxyimidazo[1,2-α]pyridine derivative 2. The unique screening lead (2) was discovered b