173194-95-1

Basic information

• Product Name: 6-HYDROXY-2-NAPHTHALENEBORONIC ACID
• Synonyms: 6-HYDROXYNAPHTHALENE-2-BORONIC ACID;6-HYDROXY-2-NAPHTHALENEBORONIC ACID;6-HYDROXY-2-NAPHTHYLENEBORONIC ACID;AKOS BRN-0430;6-HYDROXY-2-NAPTHALENE BORONIC ACID;6-Hydroxynaphthalene-2-boronic acid 98%;6-HYDROXY-2-NAPHTALENEBORONIC ACID;6-Hydroxy-2-naphthaleneboronic acid ,98%
• CAS NO: 173194-95-1
• Molecular Formula: C₁₀H₉BO₃
• Molecular Weight: 187.99
• Product Categories: blocks;BoronicAcids;6
• Mol File: 173194-95-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 218-224°C
• Boiling Point: 458.567 °C at 760 mmHg
• Flash Point: 231.134 °C
• Appearance: /
• Density: 1.358 g/cm³
• Vapor Pressure: 3.33E-09mmHg at 25°C
• Refractive Index: 1.681
• Storage Temp.: Keep Cold
• PKA: 8.80±0.30(Predicted)
• CAS DataBase Reference: 6-HYDROXY-2-NAPHTHALENEBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-HYDROXY-2-NAPHTHALENEBORONIC ACID(173194-95-1)
• EPA Substance Registry System: 6-HYDROXY-2-NAPHTHALENEBORONIC ACID(173194-95-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 173194-95-1(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

6-Hydroxynaphthalene-2-boronic acid can be used to synthesize inhibitors for oxygenase, tyrosine and phosphoinositide kinases. Tyrosine and phosphoinositide kinases are an attractive target for developing cancer drugs.

InChI:InChI=1/C10H9BO3/c12-10-4-2-7-5-9(11(13)14)3-1-8(7)6-10/h1-6,12-14H

Upstream product

• 15231-91-1 6-bromo-naphthalen-2-ol 

Downstream Products

• 898825-94-0 C₃₂H₃₄N₂O₅ 
• 269410-21-1 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol 
• 1393534-95-6 benzyl 2-(3-(benzyloxy)-5-(6-hydroxynaphthalen-2-yl)picolinamido)acetate 
• 1355646-97-7 6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 
• 1132935-63-7 N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide 
• 1027786-50-0 6-(1-(toluene-4-sulfonyl)-indol-6-yl)-naphthalen-2-ol 
• 1332332-38-3 5-{[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl}-4-[4-(6-hydroxy-2-naphthalenyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant articles and documents

IMIDAZOPYRIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS CONTAINING SAME

An imidazopyridine derivative shown by the following formula (1).

Substituted phenylalkanoic acid derivatives and use thereof

A compound represented by the formula (I) or a salt thereof: wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R1(CH2)k— (wherein k represents 0 or an integer of 1 to 3; R1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.