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1732-99-6

4-Benzoylamino-benzoic acid isobutyl ester is a chemical compound with the molecular formula C18H19NO4. It is an ester derivative of 4-benzylaminobenzoic acid, where the carboxylic acid group is esterified with isobutanol. 4-Benzoylamino-benzoic acid isobutyl ester is characterized by its aromatic structure, featuring a benzoic acid moiety and a benzylamine group. It is known for its potential applications in pharmaceuticals and as an intermediate in the synthesis of various organic compounds. The isobutyl ester group provides increased lipophilicity, which can enhance the compound's solubility in non-polar solvents and potentially its bioavailability. This chemical is typically synthesized through the esterification of 4-benzylaminobenzoic acid with isobutanol in the presence of an acid catalyst. Due to its complex structure, it is important in the field of organic chemistry and may have implications in drug design and chemical research.

1732-99-6

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1732-99-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1732-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,3 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1732-99:
(6*1)+(5*7)+(4*3)+(3*2)+(2*9)+(1*9)=86
86 % 10 = 6
So 1732-99-6 is a valid CAS Registry Number.

1732-99-6Downstream Products

1732-99-6Relevant articles and documents

Latent Bronsted Base Solvent-Assisted Amide Formation from Amines and Acid Chlorides

Otsuka, Rikuto,Maruhashi, Kazuo,Ohwada, Tomohiko

, p. 2041 - 2057 (2018)

Weakly basic amines, including even neutral amines such as nitroaniline and aminocarboxylic acids, react with acid chlorides very efficiently in N, N -dimethylacetamide (DMAC), without addition of a base, to give the corresponding amides in high yields. The role of DMAC and related solvents as latent Bronsted bases was studied in these amidation reactions. Less basic amines, such as aromatic amines, reacted with benzoyl chloride faster than more basic aliphatic amines.

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