173207-93-7

Upstream product

• 14218-11-2 2,3,4,6-Tetra-O-benzoyl-α-D-mannopyranosyl bromide 
• 150935-65-2 phenyl 2,3,4-tri-O-benzoyl-1-thio-α-D-mannopyranoside 
• 150935-64-1 phenyl 2,3,4-tri-O-benzoyl-6-O-tert-butyldimethylsilyl-1-thio-α-D-mannopyranoside 
• 173207-92-6 phenyl 2,3,4-tri-O-benzoyl-6-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis of aliphatic O-dimannosyl amino acid building blocks for solid-phase assembly of glycopeptide libraries

The preparations of α(1,2)-, α(1,3)- and α(1,6)-linked mannose disaccharides is described.The protected α-D-Man(1-->3)-D-Man disaccharide was synthesized using the trichloroacetimidate method, while the Koenigs-Knorr procedure was employed in the preparation of the 1-->2- and 1-->6-linked disaccharides.Glycosylation of NΑ-Fmoc-Ser-OPfp , Nα-Fmoc-Thr-OPfp and Nα-Fmoc-Hyp-OPfp with the dimannosyl bromides afforded the activated building blocks, in moderate to high yield, for direct use in solid-phase synthesis of glycopeptide libraries.